Sökning: "ADRs"

Visar resultat 1 - 5 av 10 uppsatser innehållade ordet ADRs.

  1. 1. Utilizing Transformers with Domain-Specific Pretraining and Active Learning to Enable Mining of Product Labels

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Avdelningen för beräkningsvetenskap

    Författare :Erik Norén; [2023]
    Nyckelord :Machine Learning; Natural Language Processing; NLP; BERT; Active Learning; AL; Pharmacovigilance; UMC; Uppsala Monitoring Centre; Structured Product Label; SPL; Transformers; Domain-Specific Pretraining; NER; Named Entity Recognition; Adverse Drug Reaction; ADR;

    Sammanfattning : Structured Product Labels (SPLs), the package inserts that accompany drugs governed by the Food and Drugs Administration (FDA), hold information about Adverse Drug Reactions (ADRs) that exists associated with drugs post-market. This information is valuable for actors working in the field of pharmacovigilance aiming to improve the safety of drugs. LÄS MER

  2. 2. Creation of a Next-Generation Standardized Drug Groupingfor QT Prolonging Reactions using Machine Learning Techniques

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Avdelningen för systemteknik

    Författare :Jacob Tiensuu; Elsa Rådahl; [2021]
    Nyckelord :Pharmacovigilance; Adverse Drug Reactions; MedDRA; VigiBase; WHODrug Global; QT prolongation; Torsades de Pointes; Individual Case Safety Reports; Text Recognition; Standardised Drug Grouping; Multinomial Logistic Regression; BERT;

    Sammanfattning : This project aims to support pharmacovigilance, the science and activities relating to drug-safety and prevention of adverse drug reactions (ADRs). We focus on a specific ADR called QT prolongation, a serious reaction affecting the heartbeat. Our main goal is to group medicinal ingredients that might cause QT prolongation. LÄS MER

  3. 3. Brexit's effect on UK ADRs

    C-uppsats, Handelshögskolan i Stockholm/Institutionen för finansiell ekonomi

    Författare :Amanda Hellström; Felicia Nordin; [2019]
    Nyckelord :American Depositary Receipts; Brexit; Abnormal returns; Event study; Difference-in-differences;

    Sammanfattning : On June 23rd 2016, the United Kingdom (UK) voted to leave the European Union, resulting in what is often referred to as Brexit. The day after the vote, the British pound (GBP) declined to the lowest level against the US dollar in 30 years and the FTSE 100 lost around GBP 85 billion. LÄS MER

  4. 4. Degustando La Bombonera de ADRs (Tasting the ADR chocolate box)

    Kandidat-uppsats, Lunds universitet/Företagsekonomiska institutionen

    Författare :Nino Dahl Merckling; Dustin Said; Erik Sjöholm; [2018]
    Nyckelord :ADR; Latin America; Introduction Puzzle; 3-market-adjusted performance; Multivariate regression; Business and Economics;

    Sammanfattning : Title: Degustando La Bombonera de ADRs - A study on the determinants of the market-adjusted return of Latin American ADRs issued between 1999 and 2014 Seminar date: 2018-01-11 Course: FEKH89, Corporate Finance Degree Project,Undergraduate level, 15 ECTS Authors: Nino Dahl Merckling, Dustin Said, Erik Sjöholm Advisor: Anamaria Cociorva Key words: ADR, Latin America, Introduction Puzzle, 3-market-adjusted performance year Performance, Multivariate Regression Purpose: The purpose of this thesis is to analyze the medium run (defined as 36 months) market-adjusted returns of ADRs of Latin American origin issued since 1999. Through running a multivariate regression, the authors seek to establish significant relationships between the medium run returns and the seven selected independent variables. LÄS MER

  5. 5. Role of state weakness in customary conflict resolution : Case of Kenya and Tanzania

    Master-uppsats, Uppsala universitet/Institutionen för freds- och konfliktforskning

    Författare :Andrei Lahunou; [2016]
    Nyckelord :Ebharaza; Baraza; CCR; ADR; Africa;

    Sammanfattning : The only way to resolve existing conflicts, mitigate consequences and reduce risks of their reoccurrence is to have efficient instrument for justice delivering. In many weak states and areas across the globe factual absence of a state’s infrastructure, corrupt court system and unbearable litigation costs leave conflict parties no other option, but to resort to violence. LÄS MER