Sökning: "Alma Pihlblad"

Hittade 2 uppsatser innehållade orden Alma Pihlblad.

  1. 1. Development and comparison of bioanalytical methods to measure free analyte

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Alma Pihlblad; [2020]
    Nyckelord :Biotechnology; immunoassay; Gyrolab; ELISA; immunology; free analyte; overestimation; affinity; Avastin; bevacizumab; Lucentis; ranibizumab; VEGF; pharmacokinetic; pharmacodynamic;

    Sammanfattning : Free analyte is measured to be able to understand the pharmacological effects of a drug in the body, the binding to its ligand, and the effective drug level among other things. Thereby, it is important with correct measurements of free analyte, although it is not that easy to achieve since overestimations can occur. LÄS MER

  2. 2. Framtidens expressionssystem för svåruttryckta proteiner : Utvärdering av tolv expressionssystem

    Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Pontus Andersson; Selma Edenståhl; Elin Eriksson; Tora Hävermark; Jonas Nielsen; Alma Pihlblad; [2018]
    Nyckelord :Expressionssystem; proteinuttryck; Corynebacterium glutamicum; Lactococcus lactis; Pseudomonas fluorescens; Pseudoalteromonas haloplanktis; Ralstonia eutropha; Streptomyces lividans; Aspergillus; ​Chlamydomonas reinhardtii; Hansenula polymorpha; Leishmania tarentolae; ​Physcomitrella patens; suspensionsbaserade växtceller;

    Sammanfattning : Today, recombinant expression of proteins is used for a variety of purposes. One of these is the production of allergens, which are vital components in allergy diagnostics. However, traditional expression systems such as ​Escherichia coli​ and ​Pichia pastoris​ might not have the capacity to express all proteins of interest. LÄS MER