Sökning: "Bioaffy"

Hittade 3 uppsatser innehållade ordet Bioaffy.

  1. 1. Effects of antibody labeling chemistry on assays developed for the Gyrolab immunoassay platform

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Molekylär systembiologi

    Författare :Julia Dencker; [2021]
    Nyckelord :Antibodies; Labeling chemistry; Site-specific labeling; Immunoassay; Gyrolab;

    Sammanfattning : The aim of this project was to make a comparison of the effects of antibody labeling chemistries on assays developed for the Gyrolab immunoassay platform. One of the labeling techniques was a heterogenous labeling technique targeting amino groups on the antibody. LÄS MER

  3. 2. Microscale measurement of kinetic binding properties of monoclonal antibodies in solution using Gyrolab

    Magister-uppsats, Institutionen för biologisk grundutbildning

    Författare :Fredrik Johansson; [2011]
    Nyckelord :Affinity; association rate constant; Bioaffy; characterization; Gyrolab; immunoassay; kinetics; microfluidics; monoclonal antibody; screening;

    Sammanfattning : The number of monoclonal antibodies approved for therapeutic use has increased rapidlyover the last decade. As a consequence, precise and robust kinetic characterization techniquesare crucial in order to select the best suitable candidates. A kinetic characterization methodwas developed in Gyrolab with automated sample transfers. LÄS MER

  4. 3. Determination of antibody affinity and kinetic binding constants in Gyrolab Bioaffy microfluidic CD

    Uppsats för yrkesexamina på grundnivå, Institutionen för fysik, kemi och biologi

    Författare :Mikael Karlsson; [2008]
    Nyckelord :Affinity constants; Equilibrium dissociation constants; Kinetic rate constants; Immunoassay; Monoclonal antibodies; Microfluidics; Gyrolab Bioaffy; Microlaboratory; Compact disc;

    Sammanfattning : Studies of binding reactions are of highest importance in a vast number of areas of biomedicine and biotechnology. A demand for fast and accurate small-volume measurements grows stronger, partly due to the development of therapeutic antibodies. In this report, a novel method for studies of binding reactions of antibodies is described. LÄS MER