Sökning: "Gene ontology"

Visar resultat 1 - 5 av 24 uppsatser innehållade orden Gene ontology.

  1. 1. Pseudomonas aeruginosa gene expression analysis using pangenome and PAO1 reference genomes

    Master-uppsats, Lunds universitet/Examensarbeten i bioinformatik

    Författare :Yi Su; [2023]
    Nyckelord :Biology and Life Sciences;

    Sammanfattning : Development in sequencing technologies has made the analyses of genetic material much more accessible. Processing sequenced data for an accurate analysis comes with its challenges, especially with the studies in microbial in clinical in vivo samples where difficulties in the collection of these samples for sequencing could lower the quality and contamination from the human host which might affect the accuracy of downstream analysis. LÄS MER

  3. 2. Investigation of Chromatin Organization and mRNA Expression in Drug Treated Human Erythroleukemia Cells

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Anam Minhas; [2022]
    Nyckelord :Erythroleukemia cells; mRNA-seq; ATAC-seq; Doxorubicin; Vinblastine; Erytroleukemiceller; mRNA-expression; kromatin; Doxorubicin; Vinblastine;

    Sammanfattning : Syftet med detta projekt var att undersöka hur vanligt använda cancerläkemedel påverkar mRNA-uttryck och kromatinorganisation i humana erytroleukemiceller. Som modell användes K562-celler från en patient i blastocystkris (2), för att utvärdera leukemicellernas svar på cancerläkemedel vinblastin och doxorubicin. LÄS MER

  4. 3. Genomic comparison of shiga toxin-producing E. coli O157:H7 from ruminants and humans

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Linnéa Good; [2022]
    Nyckelord :;

    Sammanfattning : Shiga toxin-producing E. coli (STEC) are zoonotic pathogens that frequently colonise ruminants without them showing any symptoms. In humans, STEC cause diarrhoeal disease and occasionally leads to the life-threatening disease haemolytic-uraemic syndrome (HUS). LÄS MER

  5. 4. Investigation of the gene expression landscape of human skin wounds

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Yuen Ting Cheung; [2021]
    Nyckelord :bioinformatics; wound healing; lncRNA; long non-coding RNA;

    Sammanfattning : Wound healing is a complex physiological process. Effective wound healing enables the skin barrier function to be restored once the skin is injured. However, due to the complex nature of wounds, the mechanisms underlying tissue repair are still poorly understood. LÄS MER

  7. 5. Effects of Environmental Pollutants on Gene Expression and Cellular Pathways in Model Organism

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Shrija Srinivasan; [2021]
    Nyckelord :DEHP; Environmental Pollutants; Genomics; Plastics; Endocrine Disruptors; PPAR; Pollutants;

    Sammanfattning : The increasing use of plastics has elevated the risk of exposure to environmental pollutants such as plasticisers in the general population, making it necessary to understand the possible long term health consequences of the same. In this study we aim to understand how DEHP affects the gene expression in mice models and if it causes disruptions to its cellular pathways. LÄS MER