Sökning: "HLA"

Visar resultat 1 - 5 av 41 uppsatser innehållade ordet HLA.

  1. 1. Systematic Multi-Parametric Analysis of Acute Myeloid Leukemia (AML) Flow Cytometry Drug Screens using Flowty

    Master-uppsats, Lunds universitet/Teknisk mikrobiologi

    Författare :Augusta Jensen; [2023]
    Nyckelord :Acute myeloid leukemia; AML; cellular subpopulations; data analysis; precision medicine; Flowty; applied microbiology; Biology and Life Sciences;

    Sammanfattning : Acute myeloid leukemia (AML) is a heterogeneous disease, making it difficult to treat. The standard treatment is intensive chemotherapy and has not changed in 40 years. However, recently new drugs and as less intensive treatment regimens have been approved in the US and in Europe. However. LÄS MER

  3. 2. Priorities in Pairwise Kidney Exchanges - A Simulation Study on European Kidney Exchange Programs

    Master-uppsats, Lunds universitet/Läkarutbildningen

    Författare :Samuel Lundgren; [2023]
    Nyckelord :Kidney Exchange; Pairwise Kidney Exchange; KEP; Priority; ESRD; Kidney Transplantation; Mathematics and Statistics; Medicine and Health Sciences;

    Sammanfattning : Background: For most patients with end stage renal disease (ESRD) kidney transplantation is the best treatment option. Best outcomes are achieved with living donation. To increase access to living donation for patients who are not compatible with their living donors, Kidney Exchange Programs (KEPs) have evolved. LÄS MER

  4. 3. Phenotype and function of imiquimod-treated MUTZ-3 derived Langerhans cells in potential psoriatic 3D skin model

    Master-uppsats, Malmö universitet/Institutionen för biomedicinsk vetenskap (BMV)

    Författare :Emilie Allentoft Schousboe; [2023]
    Nyckelord :3D models; imiquimod; Langerhans cells; MUTZ-3 cell line; pro-inflammatory cytokines; psoriasis;

    Sammanfattning : Upon encounter of an antigen, epidermis-resident Langerhans cells (LCs) become activated and present the processed antigen to T cells of the draining lymph nodes, resulting in tolerogenic or inflammatory responses. In psoriasis plaques, skin homeostasis is disrupted and replaced by an inflammatory dermatitis. LÄS MER

  5. 4. Identification of Immunological Targets for Brain Cancer Immunotherapy

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Zhenda Wang; [2022]
    Nyckelord :Cancer immunotherapy; brain cancer; neoantigen; MHC HLA; TCR;

    Sammanfattning : Background Cancer immunotherapy has yielded many successes. Yet to some hard-to-treat brain tumors, such as glioblastoma multiforme (GBM) and diffuse intrinsic pontine glioma (DIPG), it still lacks substantial improvement. Neoantigens resulting from mutations in malignant cells are the key targets for employing adoptive cell therapies. LÄS MER

  7. 5. Synchronous vs Asynchronous calls and Flow Control for HLA 4

    M1-uppsats, Linköpings universitet/Institutionen för datavetenskap

    Författare :David Frisén; [2022]
    Nyckelord :HLA; Federate Protocol; Synchronous; Asynchronous;

    Sammanfattning : HLA is a standard for distributed simulations where many small simulations connect to each other to create a bigger simulation. As networking technologies have evolved the requirements for the simulations. This includes running certain simulations to communicate over Wide Area, 4G, and 5G networks. LÄS MER