Sökning: "NK-cells"

Visar resultat 1 - 5 av 20 uppsatser innehållade ordet NK-cells.

  1. 1. Cytokine capture with beads in cytotoxicity assays in microwells

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Maxime Simon; [2023]
    Nyckelord :Microbead; Inteferon gamma; Natural Killer cells; microwell; binding-reaction model; Mikrokula; Interferon gamma; Naturliga Mördarceller; Mikrobrunn; modell för bindningsreaktion;

    Sammanfattning : Cytokines are small, secreted proteins that are important for cell signalling in theimmune system. Interferon gamma (IFN-γ) is one of the most potent cytokines thatnatural killer (NK) cells of the innate immune system secrete with both antiviral,antibacterial, and antitumoral activity. LÄS MER

  3. 2. Feedback imaging of cellular dynamics with fluorescence microscopy

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Emil Sorcini; [2022]
    Nyckelord :Tracking; Segmentation; Fluorescence microscopy; Lattice light-sheet; Cell migration; NK cells; ZEN; OAD; Experiment Feedback; Spårning; Segmentering; Fluorescensmikroskopi; Lattice light-sheet; Cellmigration; NK celler; ZEN; OAD; Experiment Feedback;

    Sammanfattning : In biology, it is common to study cultured cells (in vitro) with fluorescence time-lapse microscopy. The cells are recorded for longer period of time and can later be viewed at an accelerated speed. During the acquisition some live cells tend to migrate. LÄS MER

  4. 3. Structural features underlying antigen presentation by the non-classical MHC class Ib molecule Qa-1b

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Lejla AI-Tamimi; [2022]
    Nyckelord :immune checkpoint; NKG2A; MHC class Ib; Qdm; antibody; crystal structure;

    Sammanfattning : Blockering av NKG2A receptorn på NK - och CD8+ T celler med en anti-NKG2A antikropp, medför en aktivering av cytolytisk aktivitet, och är en lovande immunkontrollpunkt i immunterapi mot cancer. Nyligen har en TCR-liknande antikropp, EXX1, som binder till liganden för NKG2A receptorn, Qa-1b - en icke-klassisk MHC klass Ib molekyl i möss -studerats i tumör modeller in vitro. LÄS MER

  5. 4. Analysis of lymphocyte subsets and intracytoplasmic cytokines in Covid-19 patients using flow cytometry

    Kandidat-uppsats, Uppsala universitet/Institutionen för medicinsk cellbiologi

    Författare :Tuva Vredin; [2021]
    Nyckelord :Covid-19; immunology; lymphocytes; interleukins; flow cytometry.;

    Sammanfattning : Since late 2019 a new coronavirus, SARS-CoV2, has spread through the world and caused a pandemic. The virus causes the heterogenous disease Covid-19, causing flu- like symptoms for most people but can cause Acute Respiratory Distress Syndrome and fatal outcome in some patients. LÄS MER

  7. 5. Utilizing cytotoxic lymphocytes for indirect shock-and-kill strategy in HIV-1 treatment

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Joana FIlipa Furtado Milão; [2021]
    Nyckelord :HIV-1; Shock-and-kill strategy; NK cells; latency reservoir; HIV-1 treatment;

    Sammanfattning : Despite the existence of a treatment, there is still not a cure for HIV-1 infection and there arearound 700 000 deaths per year from AIDS-related diseases. A major barrier for a cure is theestablishment of latent reservoirs that are impossible to distinguish from healthy cells and thuscan escape the immune system. LÄS MER