Sökning: "Oskar Westlin"

Hittade 3 uppsatser innehållade orden Oskar Westlin.

  1. 1. Development of biophysical methods for characterization of PROTACs

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Biokemi

    Författare :Westlin Oskar; [2021]
    Nyckelord :;

    Sammanfattning : Targeting protein with the aim of ubiquitin-labelling for degradation is a new and upand coming field of drug discovery. Proteolysis targeting chimeras (PROTACs) areheterobifunctional linker molecules that connects the target molecule to an E3ubiquitin ligase, subsequent ubiquitination of the target protein initiates the proteindegradation by the proteosome system. LÄS MER

  3. 2. Antibiotic free and optimised protein production using Escherichia coli

    Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Mathias Engström; Olle Pontén; Carlsson Philip; Nadeen Bahnam; Ella Strömberg; Oskar Westlin; [2018]
    Nyckelord :TAT; recombinant protein production; optimisation; fermentation; chromatography; protein purification; filtration; excretion system; affibody; biopharmaceuticals; validation;

    Sammanfattning : Affibody® molecules are small therapeutic proteins which mimics antibody functionality. This is a report of several methods for increasing productivity and yield in recombinant production of Affibody® molecules. LÄS MER

  4. 3. Magmatic Sources and Processes Recorded by the Volcanics from the Izu Bonin Rear Arc

    Master-uppsats, Uppsala universitet/Institutionen för geovetenskaper

    Författare :John Owen Edgar; [2017]
    Nyckelord :Izu-Bonin; plagioclase; magma; strontium; thermobarometry; rear arc; Izu-Bonin; plagioklas; magma; strontium; termobarometri; bakbåge;

    Sammanfattning : The Izu rear-arc volcanism was investigated by IODP EXP350 in spring 2014. A total stratigraphy of1800 m was drilled, and contains volcaniclastic material within tuffaceous mudstone. LÄS MER