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  1. 1. APOPTOTIC EFFECTS IN RENAL CORTEX AFTER TREATMENT WITH 177LU-OCTREOTATE

    Master-uppsats,

    Författare :Michelle Andersson; [2021-05-10]
    Nyckelord :Medical physics; 177Lu-octreotate; renal cortex; kidney; QPCR; gene expression; transcriptional regulation; apoptosis;

    Sammanfattning : Purpose: The purpose of this project was to investigate gene regulation of a predetermined panel of apoptotic genes in murine renal cortex after treatment with 177Lu-octreotate after one day and seven days. Theory: The kidneys and bone marrow are the risk organs in 177Lu-octreotate treatment, but by fractioning the treatment the bone marrow recovers. LÄS MER