Sökning: "25 OH 2D3"
Visar resultat 1 - 5 av 7 uppsatser innehållade orden 25 OH 2D3.
1. Functional investigation of the potential therapeutic target gene DLG2 in an11q-deleted neuroblastoma cell line and effects of 1,25 vitamin D3 and retinoic acid combination treatments
Magister-uppsats, Högskolan i Skövde/Institutionen för biovetenskapSammanfattning : Neuroblastoma as a pediatric tumor develops in the sympathetic nervous system. DLG2 is a gene that encodes a member of the membrane-associated guanylate kinase (MAGUK) family and it resides in the chromosome region 11q. SK-N-AS is a neuroblastoma cell line with 11q deletion and consequently only one copy of the potential tumor suppressor gene DLG2. LÄS MER
2. 1,25(OH)2D3 and Prostate Cancer : The Effects on cAMP/PKA-dependent Gene Expression in LnCaP cells
Kandidat-uppsats, Institutionen för vård och naturSammanfattning : Prostate cancer is the leading male cancer form i Sweden and maybe worldwide as well. Vitamin D is synthesized in the skin following the exposure to sunlight. Researcers have long been aware of the positive effect that vitamin D3 has on prostate tumour growth. LÄS MER
3. 1,25(OH)2D3 and Initial Regulation of Smad2/3 Activity in PC-3 Prostate Cancer Cells
Magister-uppsats, Institutionen för vård och naturSammanfattning : The vitamin D metabolite 1,25(OH)2D3 has long been known to inhibit growth of prostate cancer cells and this mainly through a VDR-mediated pathway controlling target gene expression, resulting in cell cycle arrest, apoptosis and differentiation. Another major way in which 1,25(OH)2D3 inhibits cell growth in prostate cancer is via membrane-initiated steroid signalling, which triggers activation of signal cascades upon steroid binding to a receptor complex, leading to induction of genes regulating cell growth, proliferation and apoptosis. LÄS MER
4. Effects of 1,25(OH)2D3 on Smad2 Activity in PC-3 Prostate Cancer Cells
L3-uppsats, Institutionen för vård och naturSammanfattning : The vitamin D metabolite 1,25(OH)2D3 has long been known to inhibit growth of prostate cancer cells and this mainly through a VDR-mediated pathway controlling target gene expression, resulting in cell cycle arrest, apoptosis and differentiation. Another major way inwhich 1,25(OH)2D3 inhibits cell growth in prostate cancer is via membrane-initiated steroid signalling, which triggers activation of signal cascades upon steroid binding to a receptor complex, leading to induction of genes regulating cell growth, proliferation and apoptosis. LÄS MER
5. 1,25(OH)2D3 Initially Reduces TGFβ Activity in PC-3 Prostate Cancer Cells
Magister-uppsats, Institutionen för vård och naturSammanfattning : The vitamin D metabolite 1,25(OH)2D3 has long been known to inhibit growth of prostate cancer cells and this mainly through a VDR-mediated pathway controlling target gene expression, resulting in cell cycle arrest, apoptosis and differentiation. Another major way in which 1,25(OH)2D3 inhibits cell growth in prostate cancer is via membrane-initiated steroid signalling, which triggers activation of signal cascades upon steroid binding to a receptor complex, leading to induction of genes regulating cell growth, proliferation and apoptosis. LÄS MER
