Sökning: "4-1BB"
Hittade 3 uppsatser innehållade ordet 4-1BB.
1. Development of a cell killing adenovirus with a novel cytotoxic transgene
Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för immunologi, genetik och patologiSammanfattning : Cancer is among the most common causes of human deaths globally. Because of limitations and adverse effects of conventional cancer treatments, the need for new treatments is imminent. LÄS MER
2. 4-1BB is up-regulated in human mast cells, when exposed to tumor conditioned medium
L3-uppsats, SLU/Dept. of Anatomy, Physiology and BiochemistrySammanfattning : Mast cells have for a long time been known to accumulate around tumors (Maltby et al., 2009). Studies show that they may be important and sometimes essential in tumor angiogenesis, tumor growth and metastasis of tumors (Soucek, et al., 2007; Xiang et al. LÄS MER
3. Bioengineered T cells for Leukaemia and Lymphoma
Magister-uppsats, Institutionen för vård och naturSammanfattning : Cancer immunotherapy is a promising tool for treatment of malignancies. However, there are still hindrances that need to be overcome. Chimeric antigen receptors have the ability to direct immune cytotoxic cells towards tumour-associated antigens in major histocompatibility complex-independent manner. LÄS MER