Sökning: "Albin Leding"

Hittade 2 uppsatser innehållade orden Albin Leding.

  1. 1. Optimized design recommendation for first pharmacokinetic in vivo experiments for new tuberculosis drugs using pharmacometrics modelling and simulation

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaci

    Författare :Albin Leding; [2021]
    Nyckelord :Pharmacokinetics; Pharmacometrics; Pharmacology; population pharmacokinetics; physiologically-based pharmacokinetics; in vitro to in vivo extrapolation; IVIVE; PBPK; PK; popPK; tuberculosis; model informed approach; first in vivo pharmacokinetic experiment; mouse; mice; PKSim; NONMEM; in vitro; in vivo;

    Sammanfattning : Tuberculosis, the leading cause of death by a single infection disease caused by bacteria, requires long treatments and the bacteria are prone to develop drug resistance. Therefore, new efficient treatment regiments needs developing, which requires new tools for drug development. LÄS MER

  3. 2. An Investigation of Aspects Affecting Availability and Grading of High-Risk Antibiotics in Sweden. : Group 2

    Kandidat-uppsats, Uppsala universitet/Institutionen för teknikvetenskaper

    Författare :Andrea Fridberg; Albin Leding; Hanna Lundahl; Hannah Rydin; Hanna Sjölund; [2019]
    Nyckelord :;

    Sammanfattning : The Public Health Agency of Sweden published a report in 2017 listing 34 antibiotics that risk disappearing from the Swedish market, all with significant value to the Swedish healthcare. The aim of this report was to investigate the availability risk, why these risks occur and identify potential patterns. LÄS MER