Sökning: "Analytisk kemi"

Visar resultat 1 - 5 av 77 uppsatser innehållade orden Analytisk kemi.

  1. 1. Quantification of Pharmaceuticals at the sub-cellular level using the NanoSIMS

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Analytisk kemi

    Författare :Maryam Dost; [2024]
    Nyckelord :Mass spectroscopy imaging; AstraZeneca; Nanosims; Therapeutics; pharmacokinetics; pharmacodynamics; Quantitative Visualization; calibration curve; RSF; pharmacology; Data Analysis; Chemistry; Quantification; isotopes; Pharmaceuticals; subcellular; drug; drug target; nucleotide; biodistribution; Bioanalytical electrochemistry; spectroscopy; mass spectrometry; analytical separations; Analytical Chemistry; ROI; Bioanalytical Chemistry; Masspektroskopi avbildning; AstraZeneca; Nanosims; Terapeutik; farmakokinetik; farmakodynamik; Kvantitativ visualisering; kalibreringskurva; RSF; farmakologi; Dataanalys; Kemi; Kvantifiering; isotoper; Läkemedel; subcellulär; läkemedel; läkemedelsmål; bioskopisk elektrofördelning; nukleotid; bioskopisk bioskopisk distribution; masspektrometri; analytiska separationer; analytisk kemi; bioanalytisk kemi;

    Sammanfattning : Mass spectroscopy imaging (MSI) has become a vital tool in modern research due to its ability to visualize the spatial distribution of molecules within tissue samples. The collaboration between researchers at AZ, the University of Gothenburg, and Chalmers University of Technology using the NanoSIMS instrument and MSI-SIMS technology has opened up new avenues of exploration in pharmaceutical development, particularly in examining drugs and metabolites at sub-cellular levels. LÄS MER

  3. 2. Screening of HETP test conditions and resin storage solutions for HIC

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Analytisk farmaceutisk kemi

    Författare :Lise-Lotte Ronnerfors; [2023]
    Nyckelord :Hydrophobic Interaction Chromatography; Pfizer Health AB; Column packing;

    Sammanfattning : Hydrophobic interaction chromatography (HIC) is a common purification method for biological drug substances. For continuous monitoring the quality of the purification, a column performance test is carried out to test the packing of the resin. LÄS MER

  4. 3. Identification and Structural Elucidation of Cannabinoid Metabolites in Horse Urine Using UHPLC-HRMS

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Analytisk farmaceutisk kemi

    Författare :Agnes Morén; [2023]
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  5. 4. Determining caffeine and 3-caffeoylquinic acid content in artisanal processed specialty coffee varieties with different roasting grades, origins, and brewing methods

    Kandidat-uppsats, Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

    Författare :Oliver Mihajlovic; [2023]
    Nyckelord :kaffeanalys; koffein; klorogensyra; HPLC; analytisk kemi;

    Sammanfattning : Coffee is one of the most consumed beverages in the world, with about 10 million tons of coffee consumed in 2021. There are a lot of steps between the coffee tree and served beverage, as there are several processing methods each contributing to differences in fragrance, aroma, and acidity. LÄS MER

  7. 5. Optimization of a Microsome Incubation Method using Design of Experiment and Investigation of Metabolites Derived from GLPG0492 and LY2452473 : For Application in Doping Control

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Analytisk farmaceutisk kemi

    Författare :Rebecca Tillgren Ohlsson; [2023]
    Nyckelord :;

    Sammanfattning : .... LÄS MER