Sökning: "András Erdélyi"

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  1. 1. HisA mutants with minor structural differences display major functional deviations

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Struktur- och molekylärbiologi

    Författare :András Erdélyi; [2016]
    Nyckelord :;

    Sammanfattning : Even though enzymes tend to specialize on one reaction during evolution, enzyme promiscuity is an abundant phenomenon. The subject of this thesis is the Salmonella enterica N’-[(5’-phosphosoribosyl)-formimino]-5-aminoimidazole-4 carboxamide-ribonucleotide (ProFAR) isomerase (SeHisA), a (βα)8-barrel enzyme from the histidine biosynthesis that catalyzes one reaction on one substrate in one organism. LÄS MER