Sökning: "BIOKEMI"

Visar resultat 16 - 20 av 358 uppsatser innehållade ordet BIOKEMI.

  1. 16. The Binding Mechanism of Carbapenems in the Class A beta-lactamase IMI-1 : A Molecular Dynamics Study of Ligand Stability

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Biokemi

    Författare :Isabell Lindahl; [2022]
    Nyckelord :antibiotic resistance; IMI-1; betalactamase; Carbapenemase; free energy; LIE; linear interaction energy; β-lactamase; meropenem; biapenem; imipenem; active site;

    Sammanfattning : Antibiotic resistance is a global and accelerating matter. Over time, the bacteria have evolved several defense mechanisms against the antibiotics. One of the defense mechanisms is that the bacteria can produce enzymes with the ability to hydrolyze the characteristic b-lactam ring of the antibiotics. These enzymes are called b-lactamases. LÄS MER

  3. 17. Construction and Evaluation of a Cre-lox-Based Fluorescent Conjugation Tracking System

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Carl Brännström; [2022]
    Nyckelord :Antibiotic resistance; horizontal gene transfer; plasmids; conjugation; conjugational frequency; Cre loxP system;

    Sammanfattning : Plasmids are small, circular, extrachromosomal double-stranded genetic elements present in bacteria. Plasmids can replicate independently of the bacterial chromosome and play an important role as a transmitter of antibiotic resistance genes between bacteria. LÄS MER

  4. 18. Recombinant Expression of Novel Wild Type Oat Hemoglobins in Escherichia Coli

    Master-uppsats, Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Författare :Frank Rummukainen; [2022]
    Nyckelord :Recombinant technology; Protein expression; Hemoglobin; Phytoglobin; Escherichia coli; Oat; Avena sativa; Heme; Iron; Biosynthesis; Transcription; qPCR; SDS-PAGE; Fermentation; Recombination; Applied Biochemistry; Biology and Life Sciences;

    Sammanfattning : Hemoglobin is a protein transporting oxygen through our bloodstreams and is as such essential for aerobic life. Hemoglobins also exist in plants, with a wide variety of functions other than oxygen transport. LÄS MER

  5. 19. Development of biophysical assays for studies of PROTACs

    Master-uppsats, Uppsala universitet/Biokemi

    Författare :Daria Kovryzhenko; [2022]
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  7. 20. Epidemiology, Risk Factors, Hidden Gut Resistome and Characterization of Multidrug-Resistant Enterobacterales Colonizing the Intestinal Tract of Swiss Expatriates

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Pablo Porragas Paseiro; [2022]
    Nyckelord :;

    Sammanfattning : A study following long-term residents from countries with low prevalence of multidrug-resistant Enterobacterales residing in countries with high prevalence has never been done before at this scale. In this ongoing work, we analyzed the epidemiology and risk factors for colonization with multidrug-resistant Enterobacterales in 57 Swiss embassy employees and expatriates stationed worldwide by administering a questionnaire to establish facets of participants' diet, lifestyle, and medical history. LÄS MER