Sökning: "Biokemi"

Visar resultat 1 - 5 av 358 uppsatser innehållade ordet Biokemi.

  1. 1. OPTIMIZATION OF CLONE SELECTION PLATFORM FOR PRODUCTION OF RECOMBINANT PROTEINS

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Basel Yousef; [2024]
    Nyckelord :;

    Sammanfattning : Background  Biologics are type of proteins that can be produced by expression in a foreign host for medical healthcare applications in humans. Monoclonal antibodies (mAbs) are type of biologics that are designed to specifically bind to one target, with a purpose to inhibit a certain molecule that could be associated with a disease process. LÄS MER

  3. 2. Studies of broad-spectrum inhibitors against main protease of SARS-CoV-2 and other Coronaviruses

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Alexandra Stanciu; [2023]
    Nyckelord :human coronavirus 229E; SARS-CoV-2; main protease; nirmatrelvir; GC-376; compound 19;

    Sammanfattning : Coronaviruses have caused three large outbreaks in the past century. The most recent one, also still ongoing, is represented by the SARS-CoV-2/Covid-19 pandemic. Efforts have been taken to develop efficient vaccines and antivirals and one of the major virus-based targets in drug development is represented by the main protease of these viruses. LÄS MER

  4. 3. Characterization of Antigenic Properties of Two Immunogenic Proteins of Streptococcus pneumoniae 

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Mawj Jasimalsalih; [2023]
    Nyckelord :Immunogenic Proteins; PrsA; MalX; Membrane Vesicles; Protein Properties; Streptococcus pneumoniae virulence factors;

    Sammanfattning : The bacterium Streptococcus pneumoniae (pneumococcus), is considered to be a leading cause of morbidity and mortality globally, particularly in infants and the elderly. It is one of the most frequent causes of respiratory tract infections, which sporadically have the potential to develop into serious invasive symptoms including sepsis and meningitis. LÄS MER

  5. 4. Increased catalytic activity of engineered next generation mutant aldolase

    Master-uppsats, Uppsala universitet/Biokemi

    Författare :Eda Sönmez; [2023]
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  7. 5. Recombinant expression and purification of sugar beet Phytoglobins in Escherichia Coli BL21 (DE3) including metabolic engineering of the heme biosynthesis

    Master-uppsats, Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Författare :Pennie Lindblom; Olivia Geel; [2023]
    Nyckelord :Phytoglobin; Heme; δ-ALA; qPCR; SDS-PAGE; Bacterial cultivation; Escherichia coli; BvPgb1.2; ÄKTA; Applied biochemistry; Biology and Life Sciences;

    Sammanfattning : The protein hemoglobin (Hb) is vital for us humans to ensure enough oxygen replacement in the body. Hb-resembling proteins also exist in plants, these are called phytoglobins (Pgbs). Pgbs are very interesting since they can play a considerable role in the development of blood substitutes and iron supplements for human use. LÄS MER