Sökning: "Biological drugs"
Visar resultat 1 - 5 av 59 uppsatser innehållade orden Biological drugs.
1. Combining Cell Painting, Gene Expression and Structure-Activity Data for Mechanism of Action Prediction
Master-uppsats, Uppsala universitet/Nationellt resurscentrum för biologi och bioteknikSammanfattning : The rapid progress in high-throughput omics methods and high-resolution morphological profiling, coupled with the significant advances in machine learning (ML) and deep learning (DL), has opened new avenues for tackling the notoriously difficult problem of predicting the Mechanism of Action (MoA) for a drug of clinical interest. Understanding a drug's MoA can enrich our knowledge of its biological activity, shed light on potential side effects, and serve as a predictor of clinical success. LÄS MER
2. Biologiska läkemedel som behandling av patienter med ulcerös kolit : Effekten av antitumörnekrosfaktor läkemedlen-infliximab och adalimumab
Kandidat-uppsats, Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)Sammanfattning : Följande litteraturuppsats är ett examenarbete som är en del av farmaceutprogrammet vid Linnéuniversitetet. Denna uppsats är en systematisk litteraturstudie, det vill säga att arbetet är baserad på vetenskapliga rapporter och artiklar som upphämtades via pålitliga medicinska källor. LÄS MER
3. Predicting morphological effect of compounds on COVID-19 infected cells
Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Läkemedelsdesign och läkemedelsutvecklingSammanfattning : The cost of developing new drugs is high and the aim of computer-assisted drug discovery is to reduce that development cost, either through virtual screening or generating novel compounds. System biology is one approach to drug discovery where the response of a biological system is the subject of study, instead of drug target interaction. LÄS MER
4. Evaluating targeted combination therapies in EGFR wild-type non-small-cell lung cancer using mass spectrometry-based proteomics
Master-uppsats, Lunds universitet/Institutionen för immunteknologiSammanfattning : Survival for non-small cell lung cancer (NSCLC) patients has been significantly improved by epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in patients with EGFR mutations. However, certain subpopulations of NSCLC patients with EGFR wild-type (wt) status have been shown to also respond to EGFR-TKIs. LÄS MER
5. Panacea: Predicting anti-aging combinations from expression analysis
Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildningSammanfattning : Identifying interventions, such as drugs, that can counteract the effects of aging is crucial due to the complex nature of the aging process, which involves multiple biological processes. By targeting these processes, interventions have the potential to promote healthy aging. LÄS MER