Sökning: "Biophysical Chemistry"

Visar resultat 1 - 5 av 8 uppsatser innehållade orden Biophysical Chemistry.

  1. 1. The Effect of Using DMSO as a Cosolvent for Ligand Binding Studies

    Master-uppsats, Lunds universitet/Biofysikalisk kemi

    Författare :Simon Birgersson; [2019]
    Nyckelord :Galectins; Nuclear Magnetic Resonance; NMR; Biophysical Chemistry; Relaxation; CPMG; ITC; Biofysikalisk Kemi; Kärnmagnetisk resonans; Technology and Engineering; Chemistry; Biology and Life Sciences;

    Sammanfattning : DMSO sees common application as a solvent for studies of synthetic molecules in biological systems, in fields such as drug design. Despite this, the possibility and nature of solvent interactions with both synthetic ligand and their target macromolecules is widely unexamined. LÄS MER

  2. 2. Recombinant expression of the cowpea chlorotic mottle virus

    Kandidat-uppsats, Lunds universitet/Kemiska institutionen

    Författare :Amanda Willas; [2019]
    Nyckelord :Biokemi; Biochemistry; Viruskapsid; Viruscaspid; CCMV; Chemistry;

    Sammanfattning : All viruses are composed of both genetic material and a capsid. The capsid is composed by identical protein subunits and the purpose is protection of the genetic material, in this case RNA. LÄS MER

  3. 3. Collective behaviour in suspensions of pushers and pullers

    Master-uppsats, Lunds universitet/Biofysikalisk kemi

    Författare :Shan Anjum; [2019]
    Nyckelord :biophysics; active matter; collective motion; microswimmers; biohydrodynamics; non-equilibrium physics; low reynolds number physics; biophysical chemistry; biofysikalisk kemi; Physics and Astronomy; Chemistry; Technology and Engineering;

    Sammanfattning : Microswimmer is a term that denotes small selfpropelling agents, such as bacteria, algea or artificial robots. Depending on the flow field they set up they can be categorized into two classes: pushers (e.g. E. LÄS MER

  4. 4. Constructing supported lipid bilayers from native cell membranes

    Uppsats för yrkesexamina på avancerad nivå, Lunds universitet/Biofysikalisk kemi

    Författare :Tommy Dam; [2018]
    Nyckelord :T cells; Model membrane systems; Supported lipid bilayers; SLB; biophysical chemistry; biofysikalisk kemi; Chemistry;

    Sammanfattning : The aim of this MSc-project was to investigate whether it is possible to incorporate native cell membrane components from Jurkat T cells into supported lipid bilayers, SLBs, to produce a model membrane system better resembling the native cell membranes in T cells. The procedure of forming native-like SLBs (nSLB) was adapted from an existing protocol and is done through the deposition of hybrid vesicles onto a cleaned glass slide. LÄS MER

  5. 5. Using Molecular Dynamics and Enhanced Sampling to Predict Binding Poses Beyond The Rigid-Docking Approximation

    Master-uppsats, Lunds universitet/Biofysikalisk kemi

    Författare :Emil Åberg; [2017]
    Nyckelord :GAFF; FXR; farnesoid X receptor; MD; computational; enhanced sampling; binding; receptor; ligand; Simulations; Reconnaissance; Metadynamics; Docking; Molecular Dynamics; Protein; AMBER; force fields; structure prediction; crystallography; collective variables; potential; bias potential; biophysical chemistry; biofysikalisk kemi; Chemistry; Technology and Engineering; Biology and Life Sciences;

    Sammanfattning : A computational method is described and tested for prediction of ligand-binding poses between the human farnesoid X receptor and a set of 36 potential agonists, provided by the D3R Grand Challenge 2016. Using tools such as Molecular Docking, Molecular Dynamics, Reconnaissance metadynamics and cluster analysis, the method is an attempt to predict the binding pose without being biased by experimental data. LÄS MER