Sökning: "Biophysical Chemistry"

Visar resultat 6 - 10 av 18 uppsatser innehållade orden Biophysical Chemistry.

  1. 6. Evaluating a coarse-grained IDP-model for structure and dynamics

    Kandidat-uppsats, Lunds universitet/Biofysikalisk kemi

    Författare :Louise Kalander; [2021]
    Nyckelord :IDP; Intrinsically disordered proteins; Histatin 5; Simulation; Biophysical chemistry; Chemistry;

    Sammanfattning : In this study a coarse-grained model of intrinsically disordered proteins (IDPs) is evaluated to determine whether the model is suitable to use for analyzing the structure and dynamics of IDPs. IDPs are proteins that lack a stable tertiary structure which gives them a flexible structure. LÄS MER

  3. 7. Towards Ca2+ Responsive Reticular Materials. An Evaluation of Suitable Conditions for Self-Assembly of the Protein S100G

    Uppsats för yrkesexamina på avancerad nivå, Lunds universitet/Biofysikalisk kemi

    Författare :Andreas Carlsson; [2021]
    Nyckelord :protein material; domain swapping; EF-hand; calbindin D9k; Ca2 dependent; aggregation; S100G; protein design; biophysical chemistry; Biology and Life Sciences;

    Sammanfattning : Att bygga material av proteiner är en konst som våra kroppar är specialister på. Men när vi medvetet försöker designa proteinmaterial, så blir det tydligt hur komplexa och svårstyrda biofysikens lagar är. LÄS MER

  4. 8. Purification Methods for Solid-State NMR Analysis of Influenza A M2[18-60]

    Uppsats för yrkesexamina på avancerad nivå, Lunds universitet/Biofysikalisk kemi

    Författare :Maxine Gripberg; [2021]
    Nyckelord :Solid-state NMR; Influenza A; M2 proton channel; Biophysical chemistry; Biology and Life Sciences; Technology and Engineering; Chemistry;

    Sammanfattning : With viral infections becoming an ever-increasing health problem in the world, the study of viral proteins is a cornerstone for understanding and preventing future pandemics. The following work shows the purification and structural characterization of the Influenza A M2 proton channel through solid-state NMR (ssNMR). LÄS MER

  5. 9. A Molecular Dynamics Simulation Study of the Protein Stability of Reteplase in Formulation with Various Excipients during Freeze-Drying Processing

    Uppsats för yrkesexamina på avancerad nivå, Lunds universitet/Biofysikalisk kemi

    Författare :Gabriella Björkengren; [2021]
    Nyckelord :Biophysical chemistry; protein stability; molecular dynamics simulation; Chemistry;

    Sammanfattning : The purpose of this project was to investigate protein stabilization by formulation excipients during the process of freeze-drying using Molecular Dynamics (MD) simulation. A recombinant therapeutic protein, Reteplase, was used as a model and the study focused on a comparative analysis of two excipients, arginine and tranexamic acid (TXA), as included in commercially available formulations of Reteplase. LÄS MER

  7. 10. Development of Next-Generation Optical Tweezers : The New Swiss Army Knife of Biophysical and Biomechanical Research

    Master-uppsats, Umeå universitet/Institutionen för fysik

    Författare :Daniel Nilsson; [2020]
    Nyckelord :optical tweezers; optical fiber tweezers; optical fiber; optical trapping; manipulation; optical force; cell trapping; biophysical; physicochemical; biomechanical; research; next-generation; raman spectroscopy; holographic optical tweezers;

    Sammanfattning : In a time when microorganisms are controlling the world, research in biology is more relevant than ever and this requires some powerful instruments. Optical tweezers use a focused laser beam to manipulate and probe objects on the nano- and microscale. LÄS MER