Sökning: "CEACAM6"

Hittade 1 uppsats innehållade ordet CEACAM6.

  1. 1. Selection and characterization of bispecific ADAPT molecules for enhanced biodistribution in cancer therapy

    Master-uppsats, KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Författare :Jesper Borin; [2020]
    Nyckelord :ABD; ADAPT; HER2; CEACAM6; HSA; Phage display; Cancer therapy; Spatial bispecificity; Half-life extension; Biodistribution;

    Sammanfattning : Established biopharmaceuticals such as antibodies and derivatives thereof are relatively large. In cancer therapy, this creates a steep drug concentration gradient within tumors, leaving cells far from blood vessels effectively untreated. LÄS MER