Sökning: "CHK1 2"

Hittade 2 uppsatser innehållade orden CHK1 2.

1. 1. Investigation of drug-induced cell cycle responses in high-risk neuroblastoma

   Master-uppsats, KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

   Författare :Maryam Sahi; [2020]
   Nyckelord :Neuroblastoma; chemotherapy resistance; cell cycle arrest; cisplatin; doxorubicin; ATM; Chk1; Wee1; Neuroblastom; kemoterapiresistans; cellcykelarrest; cisplatin; doxorubicin; ATM; Chk1; Wee1;

   Sammanfattning : The childhood cancer neuroblastoma mostly affects children under the age of 2 and comprises 6% of all childhood cancers. Neuroblastoma has very diverse phenotypes caused by both inter- and intra-tumour heterogeneities. The phenotypes are classified as being either low- or high-risk. LÄS MER

3. 2. Mapping the Expression of Cyclin Dependent Kinase Inhibitors in High-Risk Neuroblastoma Cell Lines : Dynamics on Cell-Fate Decisions on Proliferation/Cell Cycle Arrest

   Master-uppsats, KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

   Författare :Ximena López Lorenzo; [2020]
   Nyckelord :Neuroblastoma; NMYC; p53; cell cycle checkpoint; inhibition; regrowth; p21; p27; SKP2; CHK1 2; Neuroblastoma; NMYC; p53; cellcykel checkpoint; hämning; återväxt; p21; p27; SKP2; CHK1 2;

   Sammanfattning : Poor prognosis for high-risk neuroblastoma patients makes it necessary to find novel treatmentstrategies. This work aims to understand the cell cycle behavior of various high-riskneuroblastoma cell lines following chemotherapy treatment. LÄS MER