Sökning: "Caco-2"

Visar resultat 1 - 5 av 10 uppsatser innehållade ordet Caco-2.

  1. 1. Improving Caco-2 permeability assay for lipophilic compounds with poor mass-balance using PC-silica beads in the BL chamber

    Master-uppsats, Uppsala universitet/Institutionen för farmaci

    Författare :Rejeen Mohammedamin; [2022]
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  3. 2. Improving Caco-2 cell permeability assay using phospholipid covered silica beads

    Uppsats för yrkesexamina på grundnivå, Uppsala universitet/Institutionen för farmaci

    Författare :Lana Faradj; [2021]
    Nyckelord :permeability; Caco-2; recovery; lipophilic; phosphatidylcholine; silica beads; peptide; plastic binding; bovine serum albumin;

    Sammanfattning : The Caco-2 cell assay is widely used for in vitro permeability measurements. However, a draw back with the assay that this study will focus on improving, is compound adsorption to the plastic material. Lipophilic compounds such as Cyclosporin A and Peptide J, that will be used in this study, tend to bind to the plastic material in the assay. LÄS MER

  4. 3. Characterization of Giardia intestinalis PAMPs and localization of Giardia’s secretome proteins during infection

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Rafael Marques; [2021]
    Nyckelord :Excretory-secretory products ESP ; Variable surface proteins VSPs ; High cysteine membrane proteins HCMPs ; Tenascins; Pathogen-associated molecular patterns PAMPs ; Host-parasite interactions;

    Sammanfattning : Giardia intestinalis is a unicellular protozoan parasite responsible for 280 million gastrointestinal infections every year. When colonizing its host, Giardia interacts closely with the small intestine epithelium by attaching to enterocytes and releasing multiple proteins to the extracellular environment. LÄS MER

  5. 4. Automated Permeability Assays for Caco-2 and MDCK Cells

    Magister-uppsats, Uppsala universitet/Institutionen för farmaci

    Författare :Hany Zitto; [2021]
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  7. 5. Toxicological screening of imidazolium based ionic liquids

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Joakim Stenström; [2020]
    Nyckelord :biology; molecular toxicology; ionic liquids; imidazolium based ionic liquids; toxicology; environmental toxicology;

    Sammanfattning : Ionic liquids are salts that are in liquid form at room temperature. These compounds have been suggested to be environmentally friendly and are proposed to be replacements for commercially available solvents used in laboratory operations today. LÄS MER