Sökning: "Cancer markers"

Visar resultat 1 - 5 av 56 uppsatser innehållade orden Cancer markers.

  1. 1. Radiotherapy treatment strategy for prostate cancer with lymph node involvement

    Master-uppsats, Umeå universitet/Institutionen för fysik

    Författare :Amanda Östensson; [2023]
    Nyckelord :Radiotherapy; prostate cancer; lymph node; gold fiducial marker; multiple target;

    Sammanfattning : Radiotherapy is a common and useful method for treating prostate cancer, often using gold fiducial markers in the prostate as guidance. However, when there is a high risk of lymph node involvement, the independent motion of volumes causes complications in patient positioning since there is a choice between position against the gold fiducial markers or the bone anatomy. LÄS MER

  3. 2. Assessment and evaluation of heterogeneity in data from immune infiltration spatial niches in lung cancer

    Kandidat-uppsats, Lunds universitet/Matematisk statistik

    Författare :Mahta Keivani Najafabadi; [2023]
    Nyckelord :Mathematics and Statistics;

    Sammanfattning : The protein biomarker expressions in three types of sampled immune INFILTration spatial niches in lung cancer tissue were measured using the new technology Digital Spatial Profiler (DSP). The three types of immune INFILTration that were observed in lung tumors were STROMA identified as immune cells separate from tumor cells, Tertiary lymphoid structures (TLS) identified as dense structures of organized immune cells and finally Infiltraterate where immune cells dispersed among and in direct contact with tumor cells (INFILT). LÄS MER

  4. 3. Detection and quantification of post-translational modifications in non-invasive samples : Phosphoproteins as biomarkers and a market analysis of protein quantification technologies

    Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Sammi Baudin; Hillevi Fjellström; Aron Kraft; Erica Lamberg; Måns Rosenbaum; Hanna Sjöstrand; [2023]
    Nyckelord :Phorphorylation; Proteomics; Biomarkers; Phosphoproteins; PTM; Amyotrophic lateral sclerosis; ALS; Alzheimer s disease; Parkinson s disease; Cancer; xMAP; SIMOA; NULISA; PEA; ELISA; Mass spectrometry; SomaScan;

    Sammanfattning : Post-translational modifications (PTMs) of proteins can be a sign and/or cause of disease. These modified proteins have the potential to be used as biomarkers for diagnostic purposes. However, research in the field is limited. LÄS MER

  5. 4. Predicting tumour growth-driving interactions from transcriptomic data using machine learning

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Neuroonkologi och neurodegeneration

    Författare :Mathilda Stigenberg; [2023]
    Nyckelord :cancer; immunology; cell-cell interactions; deep learning; variational autoencoder; supervised variational autoencoder; tumour microenvironment; single-cell RNA sequencing; spatial transcriptomics; breast cancer; machine learning;

    Sammanfattning : The mortality rate is high for cancer patients and treatments are only efficient in a fraction of patients. To be able to cure more patients, new treatments need to be invented. Immunotherapy activates the immune system to fight against cancer and one treatment targets immune checkpoints. LÄS MER

  7. 5. Investigating the crosstalk between estrogen receptor beta in colorectal cancer and tumor-associated macrophages

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Alicia Bodin; [2023]
    Nyckelord :estrogen; macrophages; colorectal cancer; qPCR; cell culture; östrogen; makrofager; tjocktarmscancer; qPCR; cellodling;

    Sammanfattning : Tjock-och ändtarmscancer (kolorektalcancer) är den tredje vanligaste cancertypen och den näst vanligaste cancer-relaterade dödsorsaken i världen. Östrogen har visat sig ha en skyddande roll mot kolorektalcancer och östrogenreceptor beta är den dominerande östrogenreceptorn i normalt kolonepitel. LÄS MER