Sökning: "Carbapenemase"
Visar resultat 1 - 5 av 9 uppsatser innehållade ordet Carbapenemase.
1. The Binding Mechanism of Carbapenems in the Class A beta-lactamase IMI-1 : A Molecular Dynamics Study of Ligand Stability
Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/BiokemiSammanfattning : Antibiotic resistance is a global and accelerating matter. Over time, the bacteria have evolved several defense mechanisms against the antibiotics. One of the defense mechanisms is that the bacteria can produce enzymes with the ability to hydrolyze the characteristic b-lactam ring of the antibiotics. These enzymes are called b-lactamases. LÄS MER
2. Screening for carbapenemase-associated biomarkers in Klebsiella oxytoca using matrixassisted laser desorption/ionization time of flight mass spectrom
Kandidat-uppsats, Örebro universitet/Institutionen för naturvetenskap och teknikSammanfattning : Antibiotic resistant bacteria are threatening human health, and the resistance is progressingfaster than the development of new antimicrobial compounds. Antibiotic resistant infections cost enormous sums of money and resources, but most importantly human lives. LÄS MER
3. Carbapenemase Producing Enterobacteriaceae - screening and contact tracing in Region Stockholm in comparison with two other Swedish regions
Magister-uppsats, Göteborgs universitet/Institutioen för biomedicinSammanfattning : Background: Carbapenemase Producing Enterobacteriaceae (CPE) is a growing problem all around the world. Sweden is relatively spared and there are very seldom outbreaks within the health care sector. LÄS MER
4. Antibiotic combination therapies against carbapenamse producing Klebsiella pneumoniae
Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildningSammanfattning : The treatment options for multidrug resistant bacteria are dwindling and it is an important issue of research in medicine to solve. One of the more problematic bacterial species is Klebsiella pneumoniae, it can cause infections with high morbidity that are difficult to treat. LÄS MER
5. Matrix Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry som verktyg för att detektera nedbrytning av Ceftolozan/Tazobaktam orsakad av karbapenemaser
Kandidat-uppsats, Örebro universitet/Institutionen för hälsovetenskaperSammanfattning : Under senare år har en särskilt hög resistensutveckling observerats hos gramnegativa bakterier inom familjen Enterobacteriaceae. Den främsta resistensmekanismen utgör produktion av så kallade "extended-spectrum β-lactamases" (ESBL) och särskilt oroväckande är karbapenemaser (ESBLCARBA) som har förmåga att bryta ner ett flertal olika grupper av β-laktamantibiotika. LÄS MER