Sökning: "Cardiotonic steroids"

Hittade 1 uppsats innehållade orden Cardiotonic steroids.

  1. 1. Ouabain Toxicity -Selectivity Towards Renal Cancer Cells

    Master-uppsats, KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Författare :Emma Magnusson; [2020]
    Nyckelord :Cardiotonic steroids; ouabain; Na K -ATPase; cytotoxicity; renal cancer; apoptosis; Kardiotoniska steroider; ouabain; Na K -ATPase; cytotoxicitet; njurcancer; apoptos;

    Sammanfattning : Ouabain and other cardiotonic steroids are known to inhibit Na + ,K + -ATPase (NKA), theion pump responsible for the ionic gradient across the plasma membrane. These steroidsdisplay a selective toxicity towards several tumour cells in comparison to primary humancells, however, the mechanism behind this is not yet understood. LÄS MER