Sökning: "Cell fusion"

Visar resultat 1 - 5 av 44 uppsatser innehållade orden Cell fusion.

  1. 1. Combining Cell Painting, Gene Expression and Structure-Activity Data for Mechanism of Action Prediction

    Master-uppsats, Uppsala universitet/Nationellt resurscentrum för biologi och bioteknik

    Författare :Erik Everett Palm; [2023]
    Nyckelord :bioinformatics; deep learning; machine learning; joint model; tabular data; image data;

    Sammanfattning : The rapid progress in high-throughput omics methods and high-resolution morphological profiling, coupled with the significant advances in machine learning (ML) and deep learning (DL), has opened new avenues for tackling the notoriously difficult problem of predicting the Mechanism of Action (MoA) for a drug of clinical interest. Understanding a drug's MoA can enrich our knowledge of its biological activity, shed light on potential side effects, and serve as a predictor of clinical success. LÄS MER

  3. 2. Traffic State Estimation on Swedish Highways : Model Comparison using Multisource Data

    Master-uppsats, KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Författare :Jiaqi Xu; [2023]
    Nyckelord :Traffic State Estimation; Macroscopic Traffic Model; Extended Kalman Filter; Particle Filter; Data Fusion; Trafiklägesuppskattning; Makroskopisk trafikmodell; Utökad Kalman-filter; Partikelfilter; Datafusion;

    Sammanfattning : Due to the escalating demand for traffic information and management, the significance of traffic state estimation, which involves the assessment of traffic conditions on road segments with limited measurement data, is increasing. Two primary estimation methods are model-driven and data-driven. LÄS MER

  4. 3. Adaptive Welding Trials – Into Robotic Systems : A pre-welding study to see the possibilities and challenges for adaptive welding implementation

    Master-uppsats, KTH/Produktionsutveckling

    Författare :Holger Johansson; [2023]
    Nyckelord :;

    Sammanfattning : This diploma project investigates a practical approach to adaptive welding. The goal was to evaluate the possibility for implementation of adaptive welding, and the diploma work comprised theoretical work and evaluations of adaptive welding of one of the welds on a front frame. LÄS MER

  5. 4. Phenotypic profiling and drug screening in Rhabdomyosarcoma cell lines

    Master-uppsats, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Författare :Laura Martina Lang; [2022]
    Nyckelord :Rhabdomyosarcoma; Phenotypic profiling; Phenotypic drug screening;

    Sammanfattning : Rhabdomyosarcoma (RMS) is a type of soft tissue sarcoma that mainly occurs in children. RMS can be divided into two subtypes embryonal (ERMS) and alveolar (ARMS). The ARMS subtype can be especially aggressive when a balanced chromosomal translocation is present. LÄS MER

  7. 5. Toward prototyping metabolic pathways in cyanobacteria using cell extracts

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Amina Bensabra; [2022]
    Nyckelord :cyanobacteria; metabolic engineering; cell-free metabolic engineering; enzymes; sustainability; cyanobakterier; metabolisk genteknik; syntetisk biologi; enzymer; hållbar bioproduktion;

    Sammanfattning : Cyanobakterier är intressanta mikroorganismer för produktion av biobränslen från solljus, vatten och atmosfärisk koldioxid och anses därför vara potentiella mikrobiella cellfabriker. Men på grund av långsam tillväxt och låg produktion är genteknologi processen intensiv och tidskrävande för cyanobakterier. LÄS MER