Sökning: "Cell sorting"

Visar resultat 1 - 5 av 25 uppsatser innehållade orden Cell sorting.

  1. 1. Combining doxorubicin and gemcitabine with targeted drugs as a treatment option for high-risk neuroblastoma

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Alexandra Johannesson; [2023]
    Nyckelord :neuroblastoma; doxorubicin; gemcitabine; targeted drugs; ATM; neuroblastom; doxorubicin; gemcitabin; målinriktade läkemedel; ATM;

    Sammanfattning : Neuroblastom är en barncancer som uppstår ur det sympatiska nervsystemet och drabbar omkring 15 barn i Sverige varje år. Högriskvarianten är associerad med mycket hög dödlighet och risk för återfall, vilket tros ha att göra med att tumörernas ovanligt heterogena sammansättning tillåter resistenta subpopulationer att motstå konventionella behandlingsmetoder. LÄS MER

  3. 2. Automatic Recycling Sorting Unit: A platform designed to sort glass, plastic and metal

    Kandidat-uppsats, KTH/Skolan för industriell teknik och management (ITM)

    Författare :Anni Li; Agnes Agåker Karlsson; [2023]
    Nyckelord :Mechatronics; Recycling; Inductive sensor; Capacitive sensor; Loadcell; Mekatronik; Återvinning; Induktivsensor; Kapacitivsensor; Viktcell;

    Sammanfattning : This report describes the design and construction of a tilting platform for sorting household waste, limited to plastic, glass, and metal. The platform utilizes a capacitive sensor to identify if an object is placed on the platform, an inductive sensor to detect metal, and a load cell to differentiate between plastic and glass based on their weight difference. LÄS MER

  4. 3. Hypoxia and hematopoietic stem cell control with the substance Adaptaquin : An evaluation of hematopoietic stem cell’s proliferation and differentiation in artificially induced hypoxia

    Kandidat-uppsats, Malmö universitet/Institutionen för biomedicinsk vetenskap (BMV)

    Författare :Jens Christiansen; [2023]
    Nyckelord :Adaptaquin; Flow cytometry; Hematopoietic stem cells; Hypoxia; Hypoxia inducible factor; Prolyl hydroxylase; Adaptaquin; Flödescytometri; Hematopoetiska stamceller; Hypoxi; Hypoxi inducerande faktor; Prolylhydroxylas;

    Sammanfattning : Hematopoietic stem cells (HSCs) have historically been difficult to maintain ex vivo with many attempts to culture them in vitro by mimicking their natural biological environment. Providing a hypoxic environment is one way to achieve this goal and can be performed by using hypoxia stimulating compounds that inhibits the degradation of HIF1a which plays an important role in regulating hypoxia. LÄS MER

  5. 4. Single-cell RNA-seq mapping of chicken leukocytes : An investigation into single-cell transcriptomics as an alternative to traditional immunological methods within non-traditional model organisms

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Mikrobiologi och immunologi

    Författare :Matilda Maxwell; [2023]
    Nyckelord :Bioinformatics; scRNA-seq; avian; immunology; Seurat; leukocytes; chicken; gallus gallus; 10x genomics; PCA;

    Sammanfattning : The immune system is a complex infrastructure where many cells interact with each other and perform duties depending on their type and function. When using traditional immunological methods in studying non-traditional model organisms, such as birds, challenges arise. LÄS MER

  7. 5. Inducing an immunosuppressed phenotype inprimary monocytes through exposure to viralproteins.

    Kandidat-uppsats, Örebro universitet/Institutionen för medicinska vetenskaper

    Författare :Seat Foung Chiu-Lilja; [2022]
    Nyckelord :;

    Sammanfattning : Background. Sepsis has been defined as a hyperactive dysregulated inflammatory response that can lead tohigh fevers, shock and multiple organ failure. However, newer findings indicate that LPS canreprogram monocytes to adopt a suppressed immune response-phenotype leading to increasedsusceptibility and mortality in a secondary infection. LÄS MER