Sökning: "Charles Dahlsson Leitao"

Hittade 1 uppsats innehållade orden Charles Dahlsson Leitao.

1. 1. Rening av bi- och multispecifika cancer-terapeutiska affinitets-proteiner och c-terminalt modifierade anti-HER3 affibodies för avbildningsdiagnostik

   Master-uppsats, KTH/Skolan för bioteknologi (BIO)

   Författare :Charles Dahlsson Leitao; [2016]
   Nyckelord :Affibody; protein therapeutic; cancer; HER3 medical imaging; tumor targeting;

   Sammanfattning : Affibody molecules are small protein scaffolds that have been engineered to bind to a variety of targets with diversetherapeutic and diagnostic applications. In this study, an array of affibody containing therapeutic constructs,targeting HER2 and HER3, and diagnostic anti-HER3 imaging agents have been purified in preparation for subsequentcancer cell assays and imaging studies in tumour-bearing mice respectively. LÄS MER