Sökning: "Consensus module"

Hittade 5 uppsatser innehållade orden Consensus module.

1. 1. Climate-neutral buildings – Impact of existing definitions on building design

   Master-uppsats, Lunds universitet/Avdelningen för Energi och byggnadsdesign; Lunds universitet/Institutionen för arkitektur och byggd miljö

   Författare :Nishat Tasnia Aive; Roberts Razna; [2022]
   Nyckelord :Climate neutrality; Climate-neutral buildings; Climate impact; Climate compensation measures; Climate-neutral certifications; Technology and Engineering;

   Sammanfattning : Climate change poses one of the most substantial threats to humanity today global greenhouse gas emissions are not reduced drastically in the near future, it can lead to severe consequences worldwide. To address this issue, global and national goals have been developed which aim to foster climate-neutral societies and industries. LÄS MER

3. 2. Comparing consensus modules using S2B and MODifieR

   Magister-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

   Författare :Daniel McCoy; [2019]
   Nyckelord :S2B; MODifieR; specific betweenness; betweenness centrality; disease module; module inference; asthma; arthritis;

   Sammanfattning : It is currently understood that diseases are typically not caused by rogue errors in genetics but have both molecular and environmental causes from myriad overlapping interactions within an interactome. Genetic errors, such as that seen by a single-nucleotide polymorphism can lead to a dysfunctional cell, which in turn can lead to systemic disruptions that result in disease phenotypes. LÄS MER

4. 3. Evaluating the biological relevance of disease consensus modules : An in silico study of IBD pathology using a bioinformatics approach

   Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

   Författare :Joel Ströbaek; [2019]
   Nyckelord :Bioinformatics; Disease module; Consensus module; Disease consensus module; Network medicine; Inflammatory bowel disease; Crohn s disease; Ulcerative colitis; S2B; NSC; Tetralith; MODifieR;

   Sammanfattning : Inflammatory bowel disease encompasses a variety of heterogeneous chronic inflammatory diseases that affect the gastrointestinal tract, where Crohn’s disease and ulcerative colitis are the principal examples. The etiology of these, and many other complex human diseases, remain largely unknown and therefore pose relevant targets for novel research strategies. LÄS MER

5. 4. Karakterisering av riskfaktorer kopplade till multipel skleros med hjälp av sjukdoms-moduler

   Magister-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

   Författare :Ola Bengtsson; [2019]
   Nyckelord :;

   Sammanfattning : Multiple sclerosis is a common neurological disorder, characterized by increasing disability over time for the affected patient. The disease is considered an autoimmune disorder in which the immune system causes damage to nerves in the central nervous system through demyelination and inflammation. LÄS MER

7. 5. Developing a web based tool for identification of disease modules

   Magister-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

   Författare :Emma Persson; [2018]
   Nyckelord :Modifier;

   Sammanfattning : Complex diseases such as cancer or obesity are thought to be caused by abnormalities in multiple  genes and cannot be derived to one specific location in the genome. It has been shown that  identification of disease associated genes can be made through looking at interaction patterns in a  protein‐protein interaction network, where the disease associated genes are represented in clusters,  or disease modules. LÄS MER