Sökning: "Counter-current chromatography"
Hittade 4 uppsatser innehållade orden Counter-current chromatography.
1. Simulation of periodic counter-current chromatography purification of monoclonal antibodies with column degradation
Master-uppsats, Lunds universitet/Kemiteknik (CI)Sammanfattning : The purification process of monoclonal antibodies (mAbs) for therapeutic drugs is expensive, especially the chromatography step in which the mAbs are separated from other proteins and cells present in the feed. The antibodies are separated from the feed using affinity chromatography, where only the antibodies interact with active sites within the column, whereas the rest passes through the column without stopping. LÄS MER
2. Development of a Graphical User Interface For Easier Overview of Historical Chromatography Data
Master-uppsats, Lunds universitet/Kemiteknik (CI)Sammanfattning : Chromatography is a separation technique frequently used in the purication of medicinal drugs. In studies and project at the department of chemical engineering at Lund University a large amount of data have been generated through the use of their research software Orbit and their ÄKTA chromatography system. LÄS MER
3. Towards autonomous antibody purification
Master-uppsats, Lunds universitet/Kemiteknik (CI)Sammanfattning : The vision of antibody purification is to have the whole process fully automatic. It is often desirable to have a continuous process since that reduces the costs for production and the size of the used equipment. It is necessary to supply buffer solutions to the purification steps, and as part of the vision; this should be done automatically. LÄS MER
4. A Model-based Approach to Evaluating Chromatography Capture Steps
Master-uppsats, Lunds universitet/Kemiteknik (CI)Sammanfattning : Recent advances in upstream production of biopharmaceuticals have not yet been matched by equivalent advances in the downstream processing. As chromatography is currently the primary downstream processing method in production of biopharmaceuticals new methods for multicolumn processes are being developed. LÄS MER
