Sökning: "Cristopher Ollagnier Widén"

Hittade 1 uppsats innehållade orden Cristopher Ollagnier Widén.

  1. 1. Reconstruction of Genome-Scale Metabolic Models with Concomitant Constraint-Based Modelling for Flux Prediction – a Case Study of Syngas Consuming Hydrogenophaga pseudoflava

    Master-uppsats, Lunds universitet/Teknisk mikrobiologi

    Författare :Cristopher Ollagnier Widén; [2020]
    Nyckelord :Applied Microbiology; flux-balance analysis FBA ; genome-scale metabolic model GEM ; Hydrogenophaga pseudoflava DSM 1084; KEGG; metabolic engineering; metabolic modelling; metabolic network reconstruction; RAVEN; syngas; systems biology; Technology and Engineering;

    Sammanfattning : Metabolic modelling coupled with flux-balance analysis (FBA) has become a popular tool in systems biology for quantitative predictions of metabolic processes in silico, and as an aid in metabolic engineering. Drawing upon gene-protein-reaction associations deducible from information on the genome-level, so-called genome-scale metabolic models (GEMs) are unequalled in their scope as they attempt to encapsulate the entire reactome of a species or cell type. LÄS MER