Sökning: "Crystallography"

Visar resultat 1 - 5 av 38 uppsatser innehållade ordet Crystallography.

  1. 1. A Machine Learning Approach on Analysis of Emission Spectra for Application in XFEL Experiments

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för fysik och astronomi

    Författare :Harald Agelii; [2023]
    Nyckelord :Structural biology; Machine learning; Neural networks; emission spectrum; XFEL; X-ray free electron laser; SFX; Serial femtosecond X-ray crystallography; Proteins; Diagnostics;

    Sammanfattning : In this thesis we investigate two potential applications of machine learning in the context of X-ray imaging and spectroscopy of biological samples, particularly such using X-ray free electron lasers (XFEL). We first investigate the possibility of using an emission spectrum, recorded from a sample after being probed by an incident X-ray, as a diagnostic tool. LÄS MER

  3. 2. Acoustic Focusing of Lysozyme Crystals

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Måns Junestrand; [2023]
    Nyckelord :Protein Crystals; Lysozyme Crystals; Ultrasound; Acoustic Focusing; SFX; Biomedical Physics; Proteinkristaller; Ultraljud; Lysozymkristaller; Akustisk fokusering; SFX; Biomedicinsk fysik;

    Sammanfattning : Acoustic focusing of microscale protein crystals with acoustophoresis technology could reduce clogs during experiments with the scientific technique serial femtosecond x-ray crystallography (SFX). SFX determines molecular structures of proteins, these structures are valuable in drug discovery and fundamental biomedical research. LÄS MER

  4. 3. Expression and purification of pyruvate transporting human mitochondrial pyruvate carrier (MPC) protein complex for structural studies

    Magister-uppsats, Lunds universitet/Examensarbeten i molekylärbiologi

    Författare :Markus Wendler; [2022]
    Nyckelord :Biology and Life Sciences;

    Sammanfattning : Pyruvate is one of the main molecules needed for the citric acid cycle, which produces energy in the form of ATP. The citric acid cycle reaction occurs in the mitochondrial matrix, and for pyruvate to participate in the reaction, it needs to be transported from the cytosol across the mitochondrial membranes into the mitochondrial matrix. LÄS MER

  5. 4. Optical Detector for Microfluidics

    Magister-uppsats, Högskolan i Halmstad/Akademin för informationsteknologi

    Författare :Carlos Gómez Jiménez; Jaime Gómez Jiménez; [2022]
    Nyckelord :Serial crystallography; Microfluidic device; Optical detector; Particle counting;

    Sammanfattning : This project arose from the need to filter the sampled data and eliminate non-useful information in Serial Crystallography in Microfluidic Device (MFD)by using a portable optical detector placed around the channel. By testing sixteen different configurations, always using an LED as a source and a photodiode as a light sensor, changes in the channel due to the passage of air bubbles were detected. LÄS MER

  7. 5. Automating Water Orientation in Neutron Crystallography using Convolutional Neural Networks

    Master-uppsats, Lunds universitet/Matematik LTH

    Författare :Simon Bakran; [2022]
    Nyckelord :Technology and Engineering;

    Sammanfattning : One important aspect of determining the functionality of proteins is to find the direction of the dipole moment of surrounding water molecules. This is equivalent to finding the position of the hydrogen in water, however with the current atomistic model building tools this is a tedious and time-consuming task. LÄS MER