Sökning: "DNA sampling"

Visar resultat 1 - 5 av 32 uppsatser innehållade orden DNA sampling.

  1. 1. Serum TK1 activity and SAA concentration as biomarkers to differentiate lymphoma from gastrointestinal disease in cats

    Master-uppsats, SLU/Dept. of Clinical Sciences

    Författare :Amanda Friman; [2023]
    Nyckelord :lymphoma; gastrointestinal lymphoma; feline lymphoma; inflammatory bowel disease; IBD; thymidine kinase 1; TK1; biomarker; cancer; cats;

    Sammanfattning : Alimentary lymphoma is one of the most common malignant neoplasms in the gastrointestinal (GI) tract in cats. Since the clinical signs often are identical to those of inflammatory bowel disease (IBD), and the findings on diagnostic imaging and endoscopic mucosal biopsies overlap, invasive biopsy sampling from the GI tract is needed to be able to differentiate these two diseases from each other. LÄS MER

  3. 2. Aromatic Ring Flips and Local Volume Fluctuations in BPTI

    Master-uppsats, Lunds universitet/Biofysikalisk kemi

    Författare :Simon Enbom; [2022]
    Nyckelord :Biophysical Chemistry; Molecular Dynamics; Protein Dynamics; Activation Volume; Aromatic Ring Flips; BPTI; Biology and Life Sciences; Chemistry; Technology and Engineering;

    Sammanfattning : Aromatic ring flips are a classic example of a dynamic process in proteins. Discovered decades ago, methodological limitations hindered progress at the time. Ring flips have gained new interest and experimentalists can measure the flip rate and thermodynamic quantities associated with it. LÄS MER

  4. 3. Comparison of preconditions for tooth sample collection and compositional change over time

    Master-uppsats, Umeå universitet/Institutionen för odontologi

    Författare :Sara Azadian; Lovisa Persson; [2022]
    Nyckelord :Dental plaque; bacteria; composition;

    Sammanfattning : Background The mouth can be colonized by many bacterial species that are associated with both health and disease. Bacteria analyses are an important part of diagnosing and treating dental diseases, but there is no consensus regarding which sampling method to use for these analyses. LÄS MER

  5. 4. Optimization of a sampling and analysis process to study the effects of skin care products on the microbial skin flora.

    Master-uppsats, Lunds universitet/Teknisk mikrobiologi

    Författare :Emma Gifvars; [2021]
    Nyckelord :Method development; Method optimization; Microbial skin flora; Biotechnology; PCR analysis; Quantification of bacteria; Degree project in applied microbiology; Technology and Engineering; Biology and Life Sciences;

    Sammanfattning : Vår hud är hem för en stor grupp av mikroorganismer, hudens mikroflora, som påverkar vår hälsa och vårt välbefinnande. Ändå finns det många aspekter av detta ämne som ännu är outforskade. LÄS MER

  7. 5. Training Machine Learning-based QSAR models with Conformal Prediction on Experimental Data from DNA-Encoded Chemical Libraries

    Master-uppsats, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Författare :Gökçe Geylan; [2021]
    Nyckelord :Machine Learning; DNA-Encoded Chemical Library; Support Vector Machine; Random Forest; Conformal Prediction; QSAR;

    Sammanfattning : DNA-encoded chemical libraries (DEL) allows an exhaustive chemical space sampling with a large-scale data consisting of compounds produced through combinatorial synthesis. This novel technology was utilized in the early drug discovery stages for robust hit identification and lead optimization. LÄS MER