Sökning: "Direct lineage conversion"

Hittade 1 uppsats innehållade orden Direct lineage conversion.

  1. 1. Modelling conversion of adult skin cells to neurons

    Master-uppsats, Lunds universitet/Institutionen för astronomi och teoretisk fysik; Lunds universitet/Beräkningsbiologi och biologisk fysik

    Författare :Viktor Drugge; [2018]
    Nyckelord :Human adult fibroblast; Neuron; Neural conversion; Transdifferentiation; Direct reprogramming; Direct lineage conversion; Simulation; Regulatory gene network; Gene network topology; Gene circuit; Gene dynamics; Physics and Astronomy;

    Sammanfattning : Scientists are now able to directly convert one somatic cell type into another using a procedure known as direct lineage reprogramming or transdifferentiation. In this procedure, transcription factors which are important for initiating a rewriting of the gene expressions are introduced in the cell. LÄS MER