Sökning: "Drug transport"

Visar resultat 1 - 5 av 33 uppsatser innehållade orden Drug transport.

  1. 1. The Quantitative Expression of Transport Proteins SLC38A1-11 in Nerve Cell Development

    Uppsats för yrkesexamina på grundnivå, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Författare :Maryam Dinar; [2023]
    Nyckelord :SLC38A1; SNAT1; SLC38A2; SNAT2; SLC38A3; SNAT3; SLC38A4; SNAT4; SLC38A5; SNAT5; SLC38A6; SNAT6; SLC38A7; SNAT7; SLC38A8; SNAT8; SLC38A9; SNAT9; SLC38A10; SNAT10; SLC38A11; SNAT11; SLC; SLC38; SNATs; SNAT; RT-qPCR; GABA; glutamine; glutamate;

    Sammanfattning : Solute carriers consist of over 400 genes and 66 subfamilies and are the largest group of membrane bound transporters. They facilitate movement of many molecules through cells and organelles and are crucial for upholding many key functions in the human body. They are also involved in the pathophysiology of several diseases. LÄS MER

  3. 2. Health Data Exchange during Transfer of Multi-morbid Elderly

    Master-uppsats, KTH/Medicinteknik och hälsosystem

    Författare :Hanan Hadi; [2023]
    Nyckelord :Ageing; Multi-morbidity; Health data; Health Information Exchange; Cooperation between region and municipality; Äldre; Multisjuka; Hälsodata; Utbyte av hälsoinformation; Samarbete mellan region och kommun;

    Sammanfattning : This project aimed to enhance communication and collaboration among care providers in Stockholm Region and Stockholm Municipality by analyzing health data in various medical record systems and identifying the data that needs to be shared to support elderly individuals with multi-morbidity. Interviews with health experts, caregivers, and policymakers, as well as a literature review, were conducted to gather data. LÄS MER

  4. 3. Structural and Functional Characterisation of the Human Mitochondrial Pyruvate Carrier

    Master-uppsats, Lunds universitet/Kemiska institutionen

    Författare :Simon Gripvall; [2023]
    Nyckelord :biochemistry; complex; MPC; proteoliposomes; pyruvate; transport; Chemistry;

    Sammanfattning : The metabolism of pyruvate in the cell is abnormally regulated in several human diseases, such as type-II diabetes, cancer and neurodegenerative disorders, in which the human mitochondrial pyruvate carrier (HuMPC) sits at a pivotal point. It transports pyruvate across the inner mitochondrial membrane and consists of two proteins, MPC1 and MPC2, and is a potential drug target against these diseases. LÄS MER

  5. 4. Toxicological analysis of Pyraclostrobin and Cyprodinilon Zebrafish larvae

    Kandidat-uppsats, Örebro universitet/Institutionen för naturvetenskap och teknik

    Författare :Kim Yeju; [2022]
    Nyckelord :gene expression; mixture effect; toxicity; pesticides; stress response;

    Sammanfattning : Cyprodinil and pyraclostrobin are widely used pesticides to protect many plants from attack of microorganisms and fungal diseases. Although cyprodinil and pyraclostrobin exist in the aquatic environment at low concentration, their leftovers in the ecosystems lead to oxidative damage and interfere development in aquatic animals at environmental-relevant concentration. LÄS MER

  7. 5. Fabrication and Characterisation of iontronic micropipette

    Master-uppsats, Linköpings universitet/Laboratoriet för organisk elektronik; Linköpings universitet/Tekniska fakulteten

    Författare :Henrik Hamrefors; [2022]
    Nyckelord :Iontronic drug delivery; Iontronic micropipette; Ion exchange membrane; AMPSA; A-HPG; Fabrication; Characterisation; Teknisk biologi; Teknisk biologi;

    Sammanfattning : The biological translation between biological and electrical signals have inspired scientists over the last decade and has opened new way of therapeutics. The group of Bioelectronics at the Laboratory of organic electronics (LOE) develops systems that utilizes this translation to reduce the gap between electronics and biology. LÄS MER