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Visar resultat 1 - 5 av 14 uppsatser som matchar ovanstående sökkriterier.

1. 1. Studies of broad-spectrum inhibitors against main protease of SARS-CoV-2 and other Coronaviruses

   Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

   Författare :Alexandra Stanciu; [2023]
   Nyckelord :human coronavirus 229E; SARS-CoV-2; main protease; nirmatrelvir; GC-376; compound 19;

   Sammanfattning : Coronaviruses have caused three large outbreaks in the past century. The most recent one, also still ongoing, is represented by the SARS-CoV-2/Covid-19 pandemic. Efforts have been taken to develop efficient vaccines and antivirals and one of the major virus-based targets in drug development is represented by the main protease of these viruses. LÄS MER

3. 2. Justering av farmakokinetiska parametrar i Hollow Fiber Experiment

   Uppsats för yrkesexamina på grundnivå, Uppsala universitet/Institutionen för farmaci

   Författare :Sima Rozbahany; [2022]
   Nyckelord :pk pd Hfs Hollow fiber model Tuberkolus;

   Sammanfattning : 1.   Sammanfattning Introduktion: Det finns idag flera allvarliga infektioner som har utmanande farmakologisk behandling, där tuberkulos är en av dem. Patogenerna som orsakar tuberkulos är svåra att behandla på grund av deras resistensmekanism, vilket gör att antibiotika inte fungerar lika effektivt längre som de gjorde tidigare. LÄS MER

4. 3. Azithromycin effects on R. subcapitata on molecular levels : Ecotoxicological study on the effects of a pollutant on chlorophyll contents, pcna and cyt P450 genes expression

   Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

   Författare :Alaa Alsayed Ahmad; [2022]
   Nyckelord :;

   Sammanfattning : Antibiotics are considered a type of antimicrobial that particularly has an impact on bacteria or fungi in humans and animals. The widespread use of common antibiotics, combined with the fact that the majority of active antibiotics and their metabolites are water-soluble, results in persistent pollution in aquatic environments, as well as a potential threat to ecosystems. LÄS MER

5. 4. Optimizing Sample Dissolution Methods of Low Water Soluble Intermediate Organic Compounds to Support Environmental Risk Assessment during Active Pharmaceutical Ingredient Manufacturing.

   Kandidat-uppsats, Örebro universitet/Institutionen för naturvetenskap och teknik

   Författare :Warda Mohammed; [2021]
   Nyckelord :Active pharmaceutical ingredient; API; total organic content; TOC; chemical oxygen demand COD; biological oxygen demand; BOD; Microtox; octanol-water partition coefficient; Kow; solubility.;

   Sammanfattning : This project focus on investigating the dissolution of low water-soluble intermediate organic compounds called active pharmaceutical ingredients (API) and organic substances that are manufactured by a pharmaceutical company, Cambrex Karlskoga in Sweden. Several dissolution methods were used and evaluated using methods including total organic carbon (TOC), chemical oxygen demand (COD), biochemical oxygen demand (BOD) and Microtox toxicity test. LÄS MER

7. 5. Efficacy of silver nanoparticles against rice blast disease and farmers perception about its management in Bangladesh

   Master-uppsats, SLU/Dept. of Biosystems and Technology (from 130101)

   Författare :Rumana Akter; [2019]
   Nyckelord :rice; blast disease; management; mycelial growth; silver nanoparticles;

   Sammanfattning : Rice blast caused by Magnaporthe grisea is one of the major and recurrent threats for sustainable rice production in Bangladesh. To mitigate this problem, the current study was aimed to investigate the efficacy of silver nanoparticles against rice blast disease and farmers’ perception or knowledge about rice blast disease management in Bangladesh. LÄS MER