Sökning: "Eva-Maria Hansson"

Hittade 1 uppsats innehållade orden Eva-Maria Hansson.

  1. 1. Towards a mechanistic explanation of insulin resistance, which incorporates mTOR, autophagy, and mitochondrial dysfunction

    Master-uppsats, Institutionen för klinisk och experimentell medicin

    Författare :Eva-Maria Hansson; [2010]
    Nyckelord :Type 2 diabetes; insulin signalling; insulin resistance; mathematical modelling; ordinary differential equations; mTOR; autophagy; mitochondria;

    Sammanfattning : Type 2 diabetes is a global disease which affects an increasing number of peopleevery year. At the heart of the disease lies insulin resistance in the target tissues,primarily fat and muscle. The insulin resistance is caused by the failure of a complexsignalling network, and several mechanistic hypotheses for this failure havebeen proposed. LÄS MER