Sökning: "Extracellular Vesicles"

Visar resultat 1 - 5 av 12 uppsatser innehållade orden Extracellular Vesicles.

  1. 1. Detection and quantification of post-translational modifications in non-invasive samples : Phosphoproteins as biomarkers and a market analysis of protein quantification technologies

    Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Sammi Baudin; Hillevi Fjellström; Aron Kraft; Erica Lamberg; Måns Rosenbaum; Hanna Sjöstrand; [2023]
    Nyckelord :Phorphorylation; Proteomics; Biomarkers; Phosphoproteins; PTM; Amyotrophic lateral sclerosis; ALS; Alzheimer s disease; Parkinson s disease; Cancer; xMAP; SIMOA; NULISA; PEA; ELISA; Mass spectrometry; SomaScan;

    Sammanfattning : Post-translational modifications (PTMs) of proteins can be a sign and/or cause of disease. These modified proteins have the potential to be used as biomarkers for diagnostic purposes. However, research in the field is limited. LÄS MER

  3. 2. Testing Coagulation Potential of Extracellular Vesicles Derived from Aortic Stenosis Patients on Human Cardiac Spheroids

    L2-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Muhammad Nafiz Ikhwan Bin Nor Fuad; [2023]
    Nyckelord :Extracellular vesicles; human aortic endothelial cells; tissue factor; TNFα; coagulation pathway; cardiac spheroids;

    Sammanfattning : Cardiovascular diseases have always been the leading cause of global morbidity and mortality. Aortic stenosis, which is a kind of cardiovascular disease has a high prevalence in elderlies that are 75 years and older. Currently, the only available treatment would be valve replacement surgery. LÄS MER

  4. 3. Comparison and optimization of extracellular vesicle (EV) capturing on functional thin films for their molecular profiling

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Prattakorn Metem; [2023]
    Nyckelord :extracellular vesicle; plasmonic nanohole array; atomic force microscopy; fluorescence analysis; extracellulära vesiklar; nanohålsuppsättning; atomkraftsmikroskopi; fluorescensanalys;

    Sammanfattning : Extracellular vesicles (EVs) are lipid bilayer encapsulated nanoparticles which have emerged as an excellent source of biomarkers for multiple diseases, including cancer. However, they are highly heterogeneous in their molecular compositions which remains a major challenge hindering the utilization of their biomarker potential. LÄS MER

  5. 4. Utsöndrade extracellulära vesiklar (EV) från hästens spolmask Parascaris univalens och deras immunmodulerande roll

    Uppsats för yrkesexamina på avancerad nivå, SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Författare :Karin Tufvesson; [2022]
    Nyckelord :Extracellulära vesiklar; Parascaris univalens; hästens spolmask; ST2; DUSP1; PCR;

    Sammanfattning : Under det senaste decenniet har ett nytt forskningsområde vuxit fram som handlar om kartläggning av extracellulära vesiklar (EV) från parasiter samt hur de kan påverka värddjurets immunförsvar. EV är lipidmembranförsedda blåsor innehållande bland annat proteiner och nukleinsyror och som används för cellkommunikation. LÄS MER

  7. 5. Analysis of Stiffness Measurement Methods on Extracellular Vesicles

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Hanna Kylhammar; [2022]
    Nyckelord :Extracellular Vesicles; AFM; Atomic Force Microscopy; Fluorescent Microscopy; Extracellulära Vesiklar; AFM; Atomkraftsmikroskopi; Fluorescensmikroskopi;

    Sammanfattning : Extracellular vesicles are important players in cell-to-cell communication and have the potential to be used as biomarkers for decease. The mechanical properties of extracellular vesicles is an active field of research, with new methods and models being developed. LÄS MER