Sökning: "Familial aggregation"

Hittade 3 uppsatser innehållade orden Familial aggregation.

  1. 1. Bri2 BRICHOS domain : Eukaryotic expression and importance of strictly conserved cysteine residues

    Master-uppsats, Linköpings universitet/Institutionen för fysik, kemi och biologi

    Författare :Lovisa Hemmingsson; [2017]
    Nyckelord :Bri2 BRICHOS; Aß; Chaperone; Amyloid fibril formation; Alzheimer disease; Eukaryotic expression; Cysteine residues;

    Sammanfattning : Alzheimer’s disease (AD), the most common form of dementia is associated with fibril formation of amyloid-ß peptides (Aß). Aß, proteolytically derived from Aß precursor protein (AßPP), is the major component of amyloid plaques in AD brains. LÄS MER

  3. 2. Why does trehalose not improve autophagy in the SOD1G93A transgenic mouse model of familial ALS?

    Uppsats för yrkesexamina på avancerad nivå, SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Författare :Karolina Karlsson; [2015]
    Nyckelord :trehalose; SOD1; amyotrophic lateral sclerosis; ALS; autophagy; plaque; neurodegeneration; trehalos; SOD1; amyotrofisk lateralskleros; ALS; autofagi; plack; neurodegeneration;

    Sammanfattning : Amyotrophic lateral sclerosis is one of the major neurodegenerative diseases, causing an ascending paralysis that usually kills the patient within a few years from disease onset. The motor neurons show aggregates of proteins which in approximately 20 % of cases of the familial form contain mutated SOD1 protein. LÄS MER

  4. 3. Familial Aggregation of Severe Preeclampsia

    Master-uppsats, Statistik

    Författare :Hassaan Tahir; [2011]
    Nyckelord :Preeclampsia; Diagnosis; Onset; Analysis; Relative Risk; Binomial regression; History; Familial aggregation; Reoccurrence; Genetic effect; Comparison; Insignificant; Gestational length; Preeclamptic pregnancy;

    Sammanfattning : It has been proved from several studies that the genetic influence has been the most significant factor for having preeclampsia (PE). Still there are many uncertainties about origin and magnitude of the genetic effects as no specific inheritance patterns have been established. LÄS MER