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1. Evaluation of soft-tissue match methods for utilization in CBCT guided adaptive radiotherapy of lung cancer patients – clinical benefits, limitations and margin determination
Master-uppsats, Lunds universitet/Medicinsk strålningsfysik, Lund; Lunds universitet/SjukhusfysikerutbildningenSammanfattning : Purpose: The aim of this study is to a) study the benefits and limitations with soft-tissue match for lung cancer patients, b) evaluate five different soft-tissue match methods, c) compare soft-tissue with bony match, d) find the stable surrogates to match on for obscured malignant lymph nodes, e) calculate CTV to PTV and OAR margins and volume of PTV for the corresponding margins, and d) study the anatomical changes associated with radiotherapy for lung cancer. Material and methods: 23 lung cancer patients (16 NSCLC, 7 SCLC) treated with radiotherapy, with 135 weekly CBCT set-up images were retrospectively matched to the planning CTs by five different match methods using the registration software Offline Review, version 10. LÄS MER
