Sökning: "Fbxw7"

Hittade 1 uppsats innehållade ordet Fbxw7.

  1. 1. Generating large-scale conditional knock-in mouse models using CRISPR/Cas9 in embryonic stem

    Master-uppsats, SLU/Dept. of Animal Breeding and Genetics

    Författare :Gus Rowan Mcfarlane; [2016]
    Nyckelord :CRISPR Cas9; conditional knock-in mice; transgenic mice; Fbxw7; colorectal cancer;

    Sammanfattning : The discovery and repurposing of CRISPR/Cas9 has revolutionized the field of genome editing and allowed for the development of mouse models with unprecedented simplicity and speed. The application of CRISPR/Cas9 in mouse embryonic stem cells represents a highly efficient and wellestablished method for generating large-scale conditional knock-in mouse models. LÄS MER