Sökning: "Fn1 Fibronectin"

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  1. 1. Actin filaments as an indicator of impaired neuronal differentiation mediated by disruption of the retinoic acid signalling pathway

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Hanin Salloum; [2022]
    Nyckelord :Retinoic acid; actin; cytoskeleton; neural progenitor C17.2 cells; neuron; Coronin 1C; Cdc42 Cdc42 effector protein 4 gene ; Fn1 Fibronectin ; Wnt pathway.;

    Sammanfattning : Retinoic acid (RA) is a well-known neurodevelopmental signaling molecule. It is reported to induce effects on neurite formation in differentiating neurons and to interfere with the actin cytoskeleton. Therefore, this project aimed to investigate the mechanisms behind effects of RA on the actin cytoskeleton of developing neurons using the C17. LÄS MER