Sökning: "Franz cell"

Visar resultat 1 - 5 av 7 uppsatser innehållade orden Franz cell.

  1. 1. Topical formulation of antimicrobials for wound care

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Författare :Ida Cederwall; [2022]
    Nyckelord :topical formulation; antibiotic resistance; topical antimicrobial formulation; topical gel; AMP; AP114; amoxicillin; wound care; poloxamer; HPMC;

    Sammanfattning : The increasing spread of antibiotic resistance among bacteria poses a major threat to the public health. There is an urge for the development of innovative formulations of existing and new antibiotics. LÄS MER

  3. 2. Study of pH effect on the skin in Franz cell by impedance spectroscopy: an attempt to model incontinence effect on the skin.

    Master-uppsats, Malmö universitet/Institutionen för biomedicinsk vetenskap (BMV)

    Författare :Megha Bhavinkumar Patel; [2022]
    Nyckelord :Artificial urine; Electrical impedance spectroscopy EIS ; Incontinence-associated dermatitis IAD ; pH; Stratum corneum SC ; Artificial urine; Electrical impedance spectroscopy EIS ; Incontinence-associated dermatitis IAD ; pH; Stratum corneum SC ;

    Sammanfattning : The human skin is the largest and most complex body organ but accessible and attractive for biomarker sampling and transdermal drug delivery. The two procedures are significantly impacted by several biophysical properties of the skin, especially the pH and stratum corneum (SC)hydration. LÄS MER

  4. 3. Permeability of fluorescently labelled proteins in silk-based skin equivalent

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaci

    Författare :Gabriel Chumpitaz Chavez; [2021]
    Nyckelord :skin equivalent; recombinant spider silk; fibroblasts; keratinocytes; permeability; Franz cells; fluorescence; bovine serum albumin; sodium fluorescein salt;

    Sammanfattning : Development of methods for studying drug delivery systems is of great significance for the improvement of topical formulations. Active compounds for topical drug delivery are often formulated into gels and creams, that can be applied onto skin surfaces. LÄS MER

  5. 4. Investigation of vitamin K interaction and transdermal delivery at skin barriers:study using k4 model

    Master-uppsats, Malmö universitet/Institutionen för biomedicinsk vetenskap (BMV)

    Författare :Alberta Agyemang; [2021]
    Nyckelord :vitamin k4; diffusion coefficient; Michaelis-Menten constant;

    Sammanfattning : Vitamin K is a fat soluble compound which is synthesized by the gut microbiota and produced in many tissues within the body. Considering its role in the liver as a cofactor for gamma carboxylase enzymes, treatment of dark circles and pigments under the eye among others. LÄS MER

  7. 5. Deep Eutectic Solvents and Their Possible Application in Transdermal Drug Delivery

    Master-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master)

    Författare :Sarah Lindblom; [2020]
    Nyckelord :Deep Eutectic Solvents; Pharmaceuticals; Transdermal drug delivery; Choline Chloride; Rheology; Formulation; BSA; Franz cell diffusion; Pharmaceutical technology; Läkemedelsteknologi; Technology and Engineering;

    Sammanfattning : Deep eutectic solvents, DES, is a type of solvent made by mixing a quaternary ammonium salt with a hydrogen bond donor at the eutectic point of the system. Most common quaternary ammonium salt is Choline Chloride, ChCl. A specific DES, Choline:CAGE has shown promise in delivering insulin through the skin of mice. LÄS MER