Sökning: "GWAS"

Visar resultat 1 - 5 av 19 uppsatser innehållade ordet GWAS.

  1. 1. Is it possible to improve the bovine immune response to mastitis using immunogenetics?

    Kandidat-uppsats, SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Författare :Emelie Björnhagen; [2019]
    Nyckelord :bovine; immunology; genetics; breeding; mastitis;

    Sammanfattning : Mastitis is a major problem for cows all over the world. For decades selection against mastitis has been performed through direct and indirect selection. Favorable outcomes of reduced mastitis incidence include: Economic gains, reduced use of antibiotics as well as improved animal welfare. LÄS MER

  2. 2. Disease modules identification in heterogenous diseases with WGCNA method

    Magister-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Naseem Ullah; [2019]
    Nyckelord :disease module; WGCNA; parameter settings;

    Sammanfattning : The widely collected and analyzed genetic data help in understanding the underlying mechanisms of heterogeneous diseases. Cellular components interact in a network fashion where genes are nodes and edges are the interactions. LÄS MER

  3. 3. Validation of the role of a SNP in the VPS35 gene and its effect on non-co-agulating milk in Swedish Red Cattle

    Master-uppsats, SLU/Dept. of Animal Breeding and Genetics

    Författare :Gro Hylén; [2018]
    Nyckelord :VPS35; genotype; SNP; SR; cow; NC-milk; MCP; genomic selection;

    Sammanfattning : From earlier studies, it is clear that nearly 20 % of the Swedish red (SR) dairy herd possess milk that doesn’t coagulate within 40 minutes after rennet addition. This is a problem when processing milk into cheese because lower cheese yield is the result of non-coagulating (NC) milk. An estimate of 17. LÄS MER

  4. 4. A canonical correlation analysis- based approach to identify causal genes in atherosclerosis

    Magister-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Crisencia Sizyoogno; [2018]
    Nyckelord :Canonical correlation analysis; Atherosclerosis; bioinformatics; CRISPR_Cas9; Phenotypes; Genotypes; GWAS; zebrafish; Cardiovascular and metabolic disease;

    Sammanfattning : Genome-wide associations studies (GWASs) have identified hundreds of loci that are strongly associated with coronary artery disease and its risk factors. However, the causal variants and genes remain unknown for the vast majority of the identified loci. LÄS MER

  5. 5. Karakterisering av genetiska riskfaktorer för dilaterad kardiomyopati hos hund

    Master-uppsats, SLU/Dept. of Animal Breeding and Genetics

    Författare :Sofia Jankulovska; [2017]
    Nyckelord :dilaterad kardiomyopati; hund; grand danois; newfoundlandshundar; genetisk associationsstudie; next-generation sequencing; digitalPCR; genetiska riskfaktorer; dilated cardiomyopathy; canine; grand danois; Newfoundlands dogs; genome-wide association studies; next-generation sequencing; digitalPCR; genetic risk factors;

    Sammanfattning : Dilaterad kardiomyopati (DCM), är en hjärtsjukdom som förekommer hos ett flertal hundraser. Etiologin är inte fastställd. Genetiska studier på hund visar att gener involverade i utvecklandet av DCM skiljer sig åt mellan olika hundraser. LÄS MER