Sökning: "GWAS"

Visar resultat 16 - 20 av 33 uppsatser innehållade ordet GWAS.

  1. 16. Karakterisering av riskfaktorer kopplade till multipel skleros med hjälp av sjukdoms-moduler

    Magister-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Ola Bengtsson; [2019]
    Nyckelord :;

    Sammanfattning : Multiple sclerosis is a common neurological disorder, characterized by increasing disability over time for the affected patient. The disease is considered an autoimmune disorder in which the immune system causes damage to nerves in the central nervous system through demyelination and inflammation. LÄS MER

  3. 17. Validation of the role of a SNP in the VPS35 gene and its effect on non-co-agulating milk in Swedish Red Cattle

    Master-uppsats, SLU/Dept. of Animal Breeding and Genetics

    Författare :Gro Hylén; [2018]
    Nyckelord :VPS35; genotype; SNP; SR; cow; NC-milk; MCP; genomic selection;

    Sammanfattning : From earlier studies, it is clear that nearly 20 % of the Swedish red (SR) dairy herd possess milk that doesn’t coagulate within 40 minutes after rennet addition. This is a problem when processing milk into cheese because lower cheese yield is the result of non-coagulating (NC) milk. An estimate of 17. LÄS MER

  4. 18. A canonical correlation analysis- based approach to identify causal genes in atherosclerosis

    Magister-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Crisencia Sizyoogno; [2018]
    Nyckelord :Canonical correlation analysis; Atherosclerosis; bioinformatics; CRISPR_Cas9; Phenotypes; Genotypes; GWAS; zebrafish; Cardiovascular and metabolic disease;

    Sammanfattning : Genome-wide associations studies (GWASs) have identified hundreds of loci that are strongly associated with coronary artery disease and its risk factors. However, the causal variants and genes remain unknown for the vast majority of the identified loci. LÄS MER

  5. 19. Karakterisering av genetiska riskfaktorer för dilaterad kardiomyopati hos hund

    Master-uppsats, SLU/Dept. of Animal Breeding and Genetics

    Författare :Sofia Jankulovska; [2017]
    Nyckelord :dilaterad kardiomyopati; hund; grand danois; newfoundlandshundar; genetisk associationsstudie; next-generation sequencing; digitalPCR; genetiska riskfaktorer; dilated cardiomyopathy; canine; grand danois; Newfoundlands dogs; genome-wide association studies; next-generation sequencing; digitalPCR; genetic risk factors;

    Sammanfattning : Dilaterad kardiomyopati (DCM), är en hjärtsjukdom som förekommer hos ett flertal hundraser. Etiologin är inte fastställd. Genetiska studier på hund visar att gener involverade i utvecklandet av DCM skiljer sig åt mellan olika hundraser. LÄS MER

  7. 20. Genetic analysis of conformation traits in Icelandic horses with focus on head morphology and body length

    Master-uppsats, SLU/Dept. of Animal Breeding and Genetics

    Författare :Veronica Felt; [2016]
    Nyckelord :Icelandic horses; conformation; SNPs; association analysis;

    Sammanfattning : In the breeding evaluation of Icelandic horses there are eight breeding goals that refer to conformation, for example head carriage. Genetic evaluation of the horse is an important part for succeeding with breeding goals and this information is taken from assessments from breeding field tests, including conformation of the horses. LÄS MER