Sökning: "Gyrolab"

Visar resultat 1 - 5 av 15 uppsatser innehållade ordet Gyrolab.

  1. 1. Development of ultra-sensitive immunoassay on Gyrolab microfluidic platform using Binding Oligo Ladder Detection : Enhancing Gyrolab biomarker assays using Exazym®

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaci

    Författare :Sam Vadi Dris; [2024]
    Nyckelord :Immnoassay; Gyrolab; TNF-alpha; Ultra-sensitive; Cavidi; Exazym; BOLD amplification; Amplification;

    Sammanfattning : Immunoassays are widely used for detection of antigens in a wide range of applications including assays in pharmaceutical development. Immunoassays are continuously improved in many aspects including automatization, miniaturization and extending the dynamic range. LÄS MER

  3. 2. Development of specific host cell protein assays

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Anna Ivert Nordén; [2023]
    Nyckelord :Gyrolab; Immunoassay; HCP;

    Sammanfattning : The manufacturing and the development of biotherapeutic drugs involves the expression of biotherapeutic proteins in a host cell expression system followed by a purification process. Bioanalytical methods to measure impurities such as host cell proteins (HCPs) are needed to obtain a robust process and a safe drug according to regulatory requirements. LÄS MER

  4. 3. Increased system sensitivity using fluorescent based immunoassays on the Gyrolab® platform

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaci

    Författare :Gabriel Lisra; [2023]
    Nyckelord :Gyrolab; fluorescence; sensitivity; immunoassays;

    Sammanfattning : Immunoassays have become an essential tool in several fields of bioanalytics with tremendous advances in sensitivity and formats seen through the last three decades. Many diseases are today diagnosed solely based on biomarker concentrations evaluated through immunoassays. LÄS MER

  5. 4. Signal amplification in a microfluidic immunoassay system via Binding Oligo Ladder Detection : Applying the Exazym® signal amplification to the Gyrolab® platform

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaci

    Författare :Daniel Wiman; [2023]
    Nyckelord :immunoassay; ultra-sensitive; signal amplification; Gyrolab; Exazym; high sensitivity; microfluidics; BOLD amplification; nucleic acid polymerisation;

    Sammanfattning : Immunoassays are analytical methods that use the highly specific binding of antibodies in order to detect and quantify an analyte. The technique has become a staple in modern biopharmaceutical research and diagnostics, however the measurement of biomarkers like dysregulated cytokines require ultra-sensitive immunoassays that can detect molecules at sub pg/mL concentrations. LÄS MER

  7. 5. Development of immunoassays that can assess therapeutic bispecific antibodies on the Gyrolab platform

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Ella Hellberg; [2023]
    Nyckelord :;

    Sammanfattning : .... LÄS MER