Sökning: "Hotan Mojarradi"

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  1. 1. Coupling of substances containing a primary amine to hyaluronan via carbodiimide-mediated amidation

    Uppsats för yrkesexamina på avancerad nivå, Institutionen för biokemi och organisk kemi

    Författare :Hotan Mojarradi; [2010]
    Nyckelord :carbodiimide; hyaluronan; optimization; EDC; NHS; tyramine;

    Sammanfattning : The purpose of this study was to investigate the carbodiimide-mediated amidation of hyaluronan (HA). The carbodiimide-mediated amidation includes the formation of a urea derivative, O-acylisourea, between the carbodiimide and a carboxylic group of HA, which a primary amine can displace, resulting in an amide bond. LÄS MER