Sökning: "Hsc70"

Hittade 1 uppsats innehållade ordet Hsc70.

  1. 1. The anti-amyloidogenic chaperone DNAJB6 and its interaction with other chaperones

    Kandidat-uppsats, Lunds universitet/Matematisk statistik; Lunds universitet/Kemiska institutionen

    Författare :Gemma Nilsson; [2020]
    Nyckelord :chaperones; DNAJB6; Hsc70; Hsp110; ATP-hydrolysis; Ab42; polyQ; biochemistry; biokemi; Chemistry;

    Sammanfattning : In order to maintain proteins’ functionality their native folding state must be preserved. Chaperones fold other proteins and DNAJ-chaperones may collaborate with Hsc70 chaperones to prevent aggregation of aggregation-prone peptides such as polyQ and Aβ42, which form fibrils in currently incurable diseases as Huntington’s and Alzheimer’s, respectively. LÄS MER