Sökning: "Hydrophilic Interaction Liquid Chromatography"

Hittade 4 uppsatser innehållade orden Hydrophilic Interaction Liquid Chromatography.

  1. 1. The initial steps in the pursuit to diagnose trimethylaminuria with liquid chromatography-tandem mass spectrometry and UniSpray ionization at CMMS

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Cristian Fransson; [2022]
    Nyckelord :;

    Sammanfattning : Trimethylaminuria is an autosomal recessive disorder characterized by a decreased oxidation capacity of trimethylamine to trimethylamine-N-oxide in the liver. The condition is diagnosed by estimating concentrations of trimethylamine and trimethylamine-N-oxide in human urine and then evaluating their respective creatinine ratios and the oxidation efficiency percentage. LÄS MER

  3. 2. Development of UPLC-MS/MS method for the determination of polar metabolites

    Kandidat-uppsats, Örebro universitet/Institutionen för naturvetenskap och teknik

    Författare :Gustav Norin; [2018]
    Nyckelord :UPLC-MS MS; HILIC; TMAO; betaine; method development;

    Sammanfattning : Trimethylamine-n-oxide (TMAO) is a metabolite found in plasma/serum in humans. Elevated levels of TMAO have been associated with several types of heart disease. It’s therefore of interest to make a simple analytical method to analyse TMAO and other metabolites that are degraded to TMAO, including betaine. LÄS MER

  4. 3. Determination of Cisplatin using Hydrophilic Interaction Liquid Chromatography (HILIC) Coupled with Inductively Coupled Plasma Mass Spectrometry (ICP-MS): A Study on Cisplatin’s Retention Mechanisms in HILIC and Uptake and Intracellular Decay Kinetics in in-vitro Grown Cells

    Master-uppsats, Kemiska institutionen

    Författare :Tinh Le; [2012]
    Nyckelord :;

    Sammanfattning : Cisplatin (cis-diamminedichloroplatinum(II), CDDP) is widely used for the treatment of several solid tumors. The antitumor property of cisplatin is generally proved that the covalent binding of cisplatin to DNA distorts the DNA structure, which leads to the death of the cancer cells. LÄS MER

  5. 4. Simultan kvantifiering av metylmalon­syra och total homocystein : En kombinationsmetod baserad på hydrofil interaktion vätskekromatografi och elektrospray jonisations­masspektrometri

    Uppsats för yrkesexamina på grundnivå, Biomedicinsk laboratorievetenskap

    Författare :Sindy Palm; [2011]
    Nyckelord :Hydrophilic Interaction Liquid Chromatography; SeQuant™ ZIC®-HILIC; masspektrometri; Metylmalonsyra; Homocystein; B-vitaminbrist; TCEP;

    Sammanfattning : .... LÄS MER