Sökning: "ICOSL"

Hittade 1 uppsats innehållade ordet ICOSL.

  1. 1. Studies of peripheral tolerance in AIRE deficient mice

    Kandidat-uppsats, Molekylär genetik

    Författare :Sabina Eriksson; [2011]
    Nyckelord :Autoimmunity; Peripheral tolerance; AIRE; APS I; DC; BAFF; ICOSL;

    Sammanfattning : Autoimmune Polyendocrine Syndrome Type 1(APS I) is a monogenic autosomal recessive autoimmune disorder which is the result of mutations in the autoimmune regulator (AIRE) gene. Symptoms of the disease include circulation of multiple organ specific autoantibodies, which leads to the breakdown of several tissues, including the adrenal cortex and the parathyroid glands. LÄS MER