Sökning: "IDH2"

Hittade 1 uppsats innehållade ordet IDH2.

  1. 1. Detection of hotspot mutations in IDH1/2 in patients withacute myeloid leukemia using Droplet Digital PCR

    Master-uppsats, Örebro universitet/Institutionen för medicinska vetenskaper

    Författare :Johanna Wågberg; [2020]
    Nyckelord :AML; IDH1; IDH2; ddPCR; NGS;

    Sammanfattning : IntroductionAcute myeloid leukemia (AML) is caused by a wide range of genetic aberrations, includingmutations within the genes that encode the enzymes isocitrate dehydrogenase 1 and 2(IDH1/2). Drugs that target mutant IDH1/2 are now available, which makes assessment of themutational status of IDH1/2 important in clinical diagnostics of AML. LÄS MER